The mortality rate and the factors realted to time of death in septic shock patients

Ta Thi Dieu Ngan, Huynh Thi Thao

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Abstract

This study was conducted to determine the mortality rate and the factors related to time of death in septic shock patients treated at the National Hospital for Tropical Diseases from 2017 to 2022. This descriptive study included patients diagnosed with septic shock according to the Sepsis-3 and SSC 2016 criteria. Early death is death within the first 3 days after admission, late death is death more than 3 days after admission. The results showed that, the early death rate was 30.4%, while late death rate was 34.6%. Upon admission, patients who passed early had significantly higher numbers of organ failures, higher SOFA scores, elevated procalcitonin and blood lactate levels, lower platelet counts, and lower blood albumin levels compared to those who passed later (p < 0.001). In the early death group, 54.4% of patients achieved a MAP > 65mmHg, and none had urine output ≥ 0.5 ml/kg/h during 6 hours of intervention, significantly lower compared to the late death group. In conclusion, at admission, SOFA score, numbers of organ failures, procalcitonin level, blood lactate level, platelet count, and albumin level were associated with early death within 3 days post-hospitalization.

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References

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