38. Chemical composition and In Vitro antimicrobial activity of essential oils from Glechoma Hederacea L
Main Article Content
Abstract
Our study aimed to investigate the chemical composition and antimicrobial activity of essential oils from Glechoma hederacea. Medicinal herbs are distilled essential oil using the steam distillation method, then the composition is studied by GC-MS, which led to the identification of 59 components, accounting for 98.03% of total oil. Among them, the main ingredients were p-sec-butylphenol (17.66%), 1,8-cineole (11.33%), germacrene D (9.97%), β-caryophyllene (9.19%), γ-terpinene (7.12 %). The results showed that essential oils from Glechoma hederacea possessed antimicrobial activity against S. aureus (Both of MSSA and MRSA) and C. albicans at MIC and MBC concentration of 1-8 µL/ML. While the essential oils were almost ineffective against E. coli and P. aeruginosa up to a concentration of 32 µL/mL. The essential oils from Glechoma hederacea can be a promising source of 1,8-cineole and germacrene D natural antibacterial for the development of new naturally derived compounds.
Article Details
Keywords
Glechoma hederacea, essential oils, antimicrobial
References
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