The spectrum of chromosomal abnormalities in patients with azoospermia and severe oligozoospermia at Buu Dien Hospiatal
Main Article Content
Abstract
Genetic abnormalities are one of the main causes of azoospermia or oligospermia in infertile men. The study aims to describe various types of chromosomal abnormalities in infertile men with azoospermia or severe oligospermia treated at Buu Dien Hospital. Karyotype assessments were conducted using peripheral blood samples analyzed by G-banding techniques. The results of180 infertile men showed that 136 patients had Klinefelter syndrome (75.56%), 5 patients had Jacobs syndrome (2.78%), 35 patients had chromosomal abnormalities (19.44%) and 4 patients had sex development disorders (male karyotype 46,XX, accounting for 2.22%). The research results are important in determining the causes of infertility and severe oligospermia in infertile men, as well as assist clinicians to select appropriate treatment regimens for reproduction. Further studies are needed to explore the long-term outcomes of assisted reproductive techniques in men with chromosomal abnormalities.
Article Details
Keywords
Chromosomal abnormality, azoospermia, oligozoospermia
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