Đánh giá hiệu quả chẩn đoán bộ sinh phẩm xét nghiệm nhanh virus cúm STANDARDTM F Influenza A/B FIA

Abstract

Rapid diagnosis of influenza is crucial for initiating early treatment, and patient isolation to prevent virus spreading within the community. This study evaluated the performance of the STANDARD^TM F Influenza A/B FIA digital kit using the automatic fluorescence reading analyzer. We tested the kit with 150 nasopharyngeal swab samples, including 50 influenza A virus-positive samples, 50 influenza B virus-positive samples, and 50 negative samples confirmed by real-time RT-PCR. Results showed that the sensitivity of the Standard F influenza A/B FIA test for flu A and B samples were 92% and 96%, respectively. We further specifically evaluated two common subtypes of influenza A virus including H1N1 and H3N2 and found the sensitivity to be 86.36% and 91.67%, respectively. The specificity for all subtypes also reached 100%. Based on the aforementioned results, the STANDARD^TM F Influenza A/B FIA kit demonstrated high sensitivity and specificity in the diagnosis of influenza,  thus is applicable for routine practice.