Đánh giá độ tương đồng, độ đồng thuận của xét nghiệm Troponin T-POCT và Troponin T-Hs trong chẩn đoán nhồi máu cơ tim

Abstract

Myocardial infarction (MI) is an emergency condition, patients need to be diagnosed early and intervene promptly. TnT-POCT can shorten the time to return results,  as such, the quality assurance for Troponin T-POCT test is very important. The study was conducted on 02 QC levels and blood samples of patients indicated for Troponin T-Hs test with the aim of confirming the value of use and evaluating the similarity and consensus of TnT-POCT test and high-sensitivity Troponin T test (TnT-Hs) in diagnosing MI. The results showed that the precision and accuracy of TnT-POCT test at QC level 2 were confirmed to be consistent with the manufacturer's published standards. The results of TnT-POCT and TnT-Hs tests were closely correlated with a correlation coefficient r of 0.92, and high agreement in the diagnosis of MI with a Kappa coefficient of 0.861. However, there was a constant error between the two methods, the median value of the difference is -14.5% which is larger than the allowable deviation, indicating that the results between the two methods are not similar.