18. Evaluation of clinical factors, computed tomography images and new pph scale to predict mortality in patients with primary pontine hemorrhage at Phu Tho Provincial General Hospital

Nguyen Huy Ngoc, Dao Quang Anh, Tran Quang Luc

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Abstract

Primary pontine haemorrhage is a severe clinical form of stroke with a high risk of disability and mortality. Therefore, we conducted a retrospective descriptive study on 48 patients with primary pontine haemorrhage at Phu Tho General Hospital from January 2020 to August 2024 to evaluate clinical mortality prognostic factors, computed tomography images and the new PPH score. The sample characteristics included 36 males (75%), with a mean age of 57.52 ± 13.12 years old; the 30-day mortality rate was 29.2%. We performed univariate and multivariate logistic regression analysis showing that GCS score < 8 (adjusted odds ratio: 23.466; 95% Confidence interval: 1.325 - 415.657) and intraventricular haemorrhage (adjusted odds ratio: 63.147; 95% Confidence interval: 3.050 - 1307.576) were independent predictors of patient mortality. The new PPH score had the best predictive value for mortality in patients with primary pontine haemorrhage when compared with the ICH score, PPH score, Chung and Park classification (Area under the receiver operating characteristic curve = 0.987 vs 0.972; 0.921; 0.875), with a sensitivity of 100% and specificity of 94.12% at a cutoff point > 1.

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References

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