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Published: 2025-02-27
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DOI: https://doi.org/10.52852/tcncyh.v187i2.3082
Issue
Vol. 187 No. 2 (2025)
Section
Các bài báo
How to Cite
Duyên, N. T., Tiến, P. T., Nghiêm, L. T., Tùng, C. V., Phúc, P. H., Điển, T. M., & Mai, T. T. C. (2025). 2. Comparison of Sysmex XN-10, Beckman Coulter DxH900 và Siemens Advia 2120i Automated Hematology Analyzers. Journal of Medical Research, 187(2), 11-21. https://doi.org/10.52852/tcncyh.v187i2.3082

2. Comparison of Sysmex XN-10, Beckman Coulter DxH900 và Siemens Advia 2120i Automated Hematology Analyzers

Nguyen Thi Duyen, Phan Thi Tien, Luong Thi Nghiem, Cao Viet Tung, Phan Huu Phuc, Tran Minh Dien, Tran Thi Chi Mai

Main Article Content

Abstract

This study aimed to assess the concordance among three automated hematology analyzers: Sysmex XN-10, Beckman Coulter DxH900, and Siemens Advia 2120i. A total of 120 pediatric blood samples were evaluated, focusing on key hematological parameters, including WBC, NEU, LYM, MONO, EO, BASO, RBC, HGB, HCT, MCV, RDW, PLT, and MPV. The analysis revealed that between the Sysmex XN-10 and Beckman Coulter DxH900 systems, only three parameters (EO, HCT, PLT) showed concordance. While most of the remaining parameters lacked agreement, they exhibited strong correlations (r² > 0.9), except for BASO and MPV, which demonstrated no correlation. Comparisons between the Sysmex XN-10 and Siemens Advia 2120i systems indicated no parameter-level agreement, with most parameters being correlated; however, MONO, BASO, and MPV showed no correlation. These findings highlight that while these systems can operate concurrently in clinical laboratories, it is crucial to establish system-specific reference ranges or utilize conversion reference ranges for correlated parameters to ensure accuracy and consistency in hematological assessments.

Article Details

Keywords

Method comparison, similarity evaluation, Sysmex XN-10, Beckman Coulter DxH900, Siemens Advia 2120i

References

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