Clinical improvement after acute phase treatment among inpatients with recurrent depressive disorder at the National Institute of Mental Health

Nguyen Van Tuan, Vu Son Tung

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Abstract

Patients in a major depressive episode when receiving treatment will often show a more or less symptoms improvement. The study was conducted on 109 in-patients with recurrent depressive disorder at the Institute of Mental Health - Bach Mai Hospital from January 2020 to December 2021. This is a case cluster analysis study. The results obtained: the average age was 48.67 ± 15.08 years old. Females accounted for 72.48%. After 4 weeks of treatment, the groups of 3 main symptoms, 7 common symptoms, 8 physical symptoms of depression all showed an average reduction of > 50% in the number of symptoms, achieving a clinical "treatment response" status. All three depression assessment scales, HAM-D, BECK, and the depression subscale of the DASS (D-DASS), showed a gradual decrease in mean scores after 2 and 4 weeks of treatment (p < 0.05). Other psychological scales predicted improvements in all aspects of mental functioning (anxiety, stress, insomnia, cognitive status, pain symptoms, quality of life) and demonstrated the effectiveness of the treatment.

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