17. Study of gastric mucosal atrophy endoscopic imaging based on Kimura-Takemoto classification
Main Article Content
Abstract
This study aimed to evaluate atrophic gastritis (AG) using the Kimura-Takemoto classification in endoscopic imaging and compare it with histopathological findings. A prospective study was conducted on 181 patients diagnosed with AG by endoscopy at the Hospital of the Post Office And Telecommunications. Endoscopic features and histopathological results were analyzed to determine the correlation between AG severity and histological lesions. The findings revealed that the most common atrophic type was C2 (28.7%), followed by C1 (25.9%) and C3 (22.7%). O1, O2, and O3 were less frequent (13.2%, 7.2%, and 2.2%, respectively). The severity of AG was classified as mild (54.7%), moderate (35.9%), and severe (9.4%). The prevalence of Helicobacter pylori infection was 65.2%, while intestinal metaplasia was observed in 46.4% of cases. A significant correlation was found between AG severity and chronic inflammation (p = 0.01), active inflammation (p < 0.01), histological atrophy (p < 0.05), intestinal metaplasia (p = 0.01), dysplasia (p < 0.05), and H. pylori infection (p < 0.05). The Kimura-Takemoto classification is a practical and effective endoscopic method for diagnosing AG.
Article Details
Keywords
Atrophic gastritis, gastric endoscopy, Helicobacter pylori
References
2. Rawla P, Barsouk A. Epidemiology of gastric cancer: global trends, risk factors and prevention. Gastroenterology Review/Przegląd Gastroenterologiczny. 2019; 14(1): 26-38.
3. Sipponen P, Maaroos H-I. Chronic gastritis. Scandinavian journal of gastroenterology. 2015; 50(6): 657-667.
4. Thái Văn Dũng, Nguyễn Văn Bình, Thái Doãn Kỳ và cộng sự. Đánh giá kết quả bước đầu điều trị tổn thương loạn sản và ung thư dạ dày sớm bằng phương pháp cắt tách hạ niêm mạc qua nội soi. Tạp chí Y học Việt Nam. 2022; 520(1A).
5. Trần Văn Hợp. Nghiên cứu giải phẫu bệnh ung thư dạ dày sau phẫu thuật. Tạp chí Khoa học Tiêu hóa Việt Nam. 2006; 1(3): 55-61.
6. Kimura K, Takemoto T. An endoscopic recognition of the atrophic border and its significance in chronic gastritis. Endoscopy. 1969; 1(03): 87-97.
7. Sugano K, Tack J, Kuipers EJ, et al. Kyoto global consensus report on Helicobacter pylori gastritis. Gut. 2015; 64(9): 1353-1367.
8. Nguyễn Thị Hòa Bình. Nghiên cứu chẩn đoán bệnh viêm dạ dày mạn tính bằng nội soi, mô bệnh học và tỷ lệ nhiễm Helicobacter pylori. Luận án Tiến sĩ Y học. 2001.
9. Mentis A-FA, Boziki M, Grigoriadis N, Papavassiliou AG. Helicobacter pylori infection and gastric cancer biology: tempering a double-edged sword. Cellular and Molecular Life Sciences. 2019; 76: 2477-2486.
10. Take S, Mizuno M, Ishiki K, et al. Baseline gastric mucosal atrophy is a risk factor associated with the development of gastric cancer after Helicobacter pylori eradication therapy in patients with peptic ulcer diseases. Journal of gastroenterology. 2007; 42: 21-27.
11. Phan Trung Nam, Nguyễn Thị Huyền Thương. Mối liên quan giữa teo niêm mạc dạ dày trên nội soi theo phân loại Kimura-Takemoto với đặc điểm mô bệnh học ở bệnh nhân viêm dạ dày mạn có Helicobacter pylori. Tạp chí Y Dược học - Trường Đại học Y Dược Huế. 2023; 1(13)
12. Alhussaini MS. Prevalence of Helicobacter pylori among patients with different gastrointestinal disorders in Saudi Arabia. Medical Journal of Indonesia. 2016; 25(4): 214-20.
13. Kimura K, Satoh K, Ido K, Taniguchi Y, Takimoto T, Takemoto T. Gastritis in the Japanese stomach. Scandinavian Journal of Gastroenterology. 1996; 31(sup214): 17-20.