The association between serum 25(OH)D levels and clinical features in children with pneumonia at E Hospital

Nguyen Thi Thuy Hong, Chu Thi Thanh Hoa

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Abstract

This study describes the relationship between serum 25-hydroxyvitamin D (25(OH)D) levels and clinical characteristics in children with pneumonia at E Hospital. The results from 93 children with pneumonia showed that 12.9% had serum 25(OH)D levels ≤ 20 ng/mL, with only 3.2% classified as vitamin D deficient. Specifically, the rate of rapid breathing in the vitamin D-deficient group is 66.7%, while it is only 46.9% in the vitamin D-sufficient group. Similarly, the rate of chest indrawing in the vitamin D-deficient group is 58.3%, higher than 28.4% in the vitamin D-sufficient group. Furthermore, children with pneumonia and vitamin D deficiency also had a higher number of lower respiratory tract infections in the past year compared to the vitamin D sufficient group. There was a significant association between 25(OH)D levels and pneumonia severity, with the vitamin D-insufficient group having 3.53-fold increased risk of developing severe pneumonia compared to the vitamin D-sufficient group.

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References

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