Update of invasive fungal diseases diagnosis in children
Main Article Content
Abstract
Invasive fungal diseases were defined as the presence of molds (filamentous fungi) or yeasts in deep tissues confirmed by culture or histopathology. The incidence of invasive fungal diseases has increased rapidly over the past 20 years. More than 90% of deaths due to invasive fungal diseases are caused by four main genera: Candida, Aspergillus, Cryptococcus, and Pneumocystis. The clinical presentation of invasive fungal infections is often severe, with diverse and nonspecific symptoms, leading to difficulties in diagnosis and delays in treatment. Additionally, the rising antifungal resistance among fungal strains contributes to persistently high mortality rates. Currently, the diagnostic criteria for invasive fungal infections in children are based on the 2019 EORTC/MSGERC consensus conference criteria (European Organization for Research and Treatment of Cancer/Fungal Infections Education and Research Group (EORTC/MSGERC). The diagnostic criteria for probable and possible invasive fungal infections are only applied to immunocompromised subjects. The criteria of this Consensus Conference are limited to subjects treated in intensive care units.
Article Details
Keywords
Invasive fungal disease, children, EORTC/MSGERC standard, 2019
References
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