Khảo sát giá trị của chỉ số huyết sắc tố hồng cầu lưới trong chẩn đoán thiếu sắt ở người bệnh thận mạn có lọc thận nhân tạo chu kỳ

Abstract

The reticulocyte hemoglobin equivalent (Ret-He) is a parameter that directly assesses iron status within red blood cells, particularly reticulocytes. This cross-sectional study was conducted on 109 patients with chronic kidney disease undergoing undergoing r hemodialysis at Thong Nhat General Hospital, Dong Nai, from February to July 2023. Iron deficiency was observed in 25.7% of the study participants, with significantly lower Ret-He levels in the iron-deficient group compared to the non-deficient group (p < 0.05). A strong correlation was found between Ret-He and both serum iron and transferrin saturation (TSAT) (p < 0.001). However, with a Ret-He cutoff value of 25pg, the sensitivity was 46.4%, specificity was 80.3%, and the area under the Receiver Operating Characteristic (ROC) curve was 0.670 - lower than traditional iron parameters. These findings suggest that Ret-He cannot independently and effectively replace conventional iron parameters in diagnosing iron deficiency in hemodialysis patients.