Clinical, paraclinical characteristics of acute cholangitis before and after percutaneous biliary drainage
Main Article Content
Abstract
This retrospective study examined 102 patients diagnosed with acute cholangitis due to cholelithiasis and treated at Hanoi Medical University between 2020 and 2024. The objective was to evaluate the clinical and paraclinical characteristics of patients before and after percutaneous biliary drainage. Acute cholangitis was classified according to the Tokyo Guidelines 2018, with 38.3% of patients classified as grade I, 39.2% as grade II, and 22.5% as grade III. Right upper quadrant abdominal pain was reported in 99% of patients. Fever, jaundice, white blood cell counts, and total bilirubin levels were significantly higher in grade III patients compared to grade II. Positive bile cultures were found in 78.4% of cases, while 52.9% had positive blood cultures. The most commonly identified pathogens were Escherichia coli, Enterococcus spp., and Pseudomonas aeruginosa. After 72 hours of percutaneous biliary drainage, most patients had no fever and there were significant reductions in white blood cell counts, C-reactive protein, liver enzymes, and bilirubin levels compared to both baseline and 24-hour post-intervention. The only complication observed was haemobilia, occurring in 4.9% of all cases. In conclusion, percutaneous biliary drainage effectively improved clinical symptoms and laboratory markers in patients with acute cholangitis due to cholelithiasis after 72 hours post-intervention.
Article Details
Keywords
Cholangitis, cholelithiasis, percutanous biliary drainage
References
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