Pediatric epilepsy categorization according to the 2017 international league against epilepsy classification at Saint Paul General Hospital
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Abstract
This study applied the 2017 International League Against Epilepsy (ILAE) classification system to categorize pediatric epilepsy patients at Saint Paul General Hospital. A cross-sectional study was conducted on 249 pediatric patients from September 2023 to August 2024. The results demonstrated that 100% of seizure onset types were classified. Focal onset seizures were the most prevalent, representing 46.3%, with focal impaired awareness seizures being the most common subtype (42.5%). Generalized-onset and unknown-onset seizures accounted for 29.7% and 23.9%, respectively. Regarding epilepsy classification, focal epilepsy was the most common type (51.8%), while generalized epilepsy and combined focal and generalized epilepsy accounted for 38.2% and 10%, respectively. Epilepsy syndromes were identified in 22.4% of cases, with benign Rolandic epilepsy being the most frequently diagnosed syndrome (7.2%). An identifiable etiology was found in 31.3% of cases, with structural brain abnormalities being the most common cause (24.5%). These findings support the feasibility of the 2017 ILAE epilepsy classification system in accurately categorizing seizure onset, thereby facilitating effective treatment planning for pediatric epilepsy patients.
Article Details
Keywords
Epilepsy, pediatric, classification, ILAE 2017
References
2. Lu VM, Vazquez S, Abou-Al-Shaar H, et al. The epidemiologic associations of food availability with national incidence and disability rates of idiopathic pediatric epilepsy. Journal of Clinical Neuroscience. 2025;131:110955.
3. Roger J, Dreifuss F, Martinez-Lage M, et al. Proposal for revised classification of epilepsies and epileptic syndromes. Epilepsia. 1989;30(4):389-399.
4. Scheffer IE, Berkovic S, Capovilla G, et al. ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology. Epilepsia. 2017;58(4):512-521.
5. Lê Đức Anh, Đào Thị Nguyệt, Nguyễn Thị Thanh Mai. Đặc điểm lâm sàng, cận lâm sàng và kết quả điều trị động kinh ở trẻ em tại Bệnh viện Nhi Thanh Hóa. Tạp chí Y học Việt Nam. 2022;516:241-244.
6. Fisher RS, Acevedo C, Arzimanoglou A, et al. ILAE official report: a practical clinical definition of epilepsy. Epilepsia. 2014;55(4):475-482.
7. Aaberg KM, Surén P, Søraas CL, et al. Seizures, syndromes, and etiologies in childhood epilepsy: The International League Against Epilepsy 1981, 1989, and 2017 classifications used in a population-based cohort. Epilepsia. 2017;58(11):1880-1891.
8. Gao H, Sander JW, Xiao Y, et al. A comparison between the 1981 and 2017 International League Against Epilepsy classification of seizure types based on an outpatient setting. Epileptic Disorders. 2018;20(4):257-264.
9. Wang F, Chen Z, Davagnanam I, et al. Comparing two classification schemes for seizures and epilepsy in rural China. European journal of neurology. 2019;26(3):422-427.
10. Warren AE, Patel AD, Helen Cross J, et al. Mobilizing a New Era in Lennox-Gastaut Syndrome Treatment and Prevention. Epilepsy Currents. 2025:15357597251321926.
11. Gauci MC, Gauci R, Ruggieri M, et al. Clinical, Genetic, EEG, Neuroimaging Insights and Conservative Treatment in Pediatric Focal Epilepsy: A Retrospective Observational Study. Journal of Clinical Medicine. 2025;14(7):2234.
12. Blazekovic A, Gotovac Jercic K, Meglaj S, et al. Genetics of pediatric epilepsy: next-generation sequencing in clinical practice. Genes. 2022;13(8):1466.