55. Factors which increase the risk of mortality in COVID-19
Main Article Content
Abstract
Since the first COVID-19 case was recorded in January 2020, Vietnam was one of the nations enduring the most severe impact of the fourth wave caused by the Delta variant, especially in Ho Chi Minh City. Understanding the risk factors for severe outcomes would identify vulnerable populations and facilitate medical decision-making. Our retrospective study observed 504 eligible COVID-19 patients admitted to an Intensive Care Center (ICU) in Ho Chi Minh City, urgently built by Bach Mai Hospital in August 2021. The study results showed that patients over 60 years old had a 3.1-fold higher risk of death than those under 60 years old. A history of diabetes was identified as a significant contributor to increased risk of death (OR = 1.646, 95% CI: 1.036 - 2.617, p = 0.035) as well as each unit increase in BMI increased the risk of death by 6.7% in patients with COVID-19.
Article Details
Keywords
COVID-19, risk of mortality, diabetes and COVID-19
References
2. Tình hình dịch bệnh truyền nhiễm và các giải pháp phòng, chống dịch. Tình hình dịch bệnh truyền nhiễm và các giải pháp phòng, chống dịch. https://vncdc.gov.vn/tinh-hinh-dich-benh-truyen-nhiem-va-cac-giai-phap-phong-chong-dich-nd17323.html. Accessed April 11, 2025.
3. Kania M, Koń B, Kamiński K, et al. Diabetes as a risk factor of death in hospitalized COVID-19 patients - an analysis of a National Hospitalization Database from Poland, 2020. Front Endocrinol (Lausanne). 2023; 14: 1161637. doi:10.3389/fendo.2023.1161637.
4. Bonanad C, García-Blas S, Tarazona-Santabalbina F, et al. The Effect of Age on Mortality in Patients With COVID-19: A Meta-Analysis With 611,583 Subjects. Journal of the American Medical Directors Association. 2020;21(7):915-918. doi:10.1016/j.jamda.2020.05.045
5. Singh R, Rathore SS, Khan H, et al. Association of Obesity With COVID-19 Severity and Mortality: An Updated Systemic Review, Meta-Analysis, and Meta-Regression. Front Endocrinol (Lausanne). 2022; 13: 780872. doi:10.3389/fendo.2022.780872.
6. Gao M, Piernas C, Astbury NM, et al. Associations between body-mass index and COVID-19 severity in 6·9 million people in England: a prospective, community-based, cohort study. The Lancet Diabetes & Endocrinology. 2021; 9(6): 350-359. doi:10.1016/S2213-8587(21)00089-9.
7. Hendren NS, de Lemos JA, Ayers C, et al. Association of Body Mass Index and Age With Morbidity and Mortality in Patients Hospitalized With COVID-19: Results From the American Heart Association COVID-19 Cardiovascular Disease Registry. Circulation. 2021; 143(2): 135-144. doi:10.1161/CIRCULATIONAHA.120.051936.
8. Obesity and Mortality Among Patients Diagnosed With COVID-19: Results From an Integrated Health Care Organization | Annals of Internal Medicine. https://www.acpjournals.org/doi/10.7326/M20-3742. Accessed April 11, 2025.
9. Kalligeros M, Shehadeh F, Mylona EK, et al. Association of Obesity with Disease Severity Among Patients with Coronavirus Disease 2019. Obesity (Silver Spring). 2020; 28(7): 1200-1204. doi:10.1002/oby.22859.
10. Trên 84% ca COVID-19 tử vong từ 50 tuổi trở lên: Cấp thiết, quyết liệt bảo vệ nhóm đối tượng nguy cơ cao - Hoạt động của lãnh đạo bộ - Cổng thông tin Bộ Y tế. https://moh.gov.vn/hoat-dong-cua-lanh-dao-bo/-/asset_publisher/TW6LTp1ZtwaN/content/tren-84-ca-covid-19-tu-vong-tu-50-tuoi-tro-len-cap-thiet-quyet-liet-bao-ve-nhom-oi-tuong-nguy-co-cao. Accessed April 11, 2025.
11. Kalligeros M, Shehadeh F, Mylona EK, et al. Association of Obesity with Disease Severity Among Patients with Coronavirus Disease 2019. Obesity (Silver Spring). 2020; 28(7): 1200-1204. doi:10.1002/oby.22859.
12. Việt Nam hiện tỷ lệ người mắc bệnh đái tháo đường đang gia tăng nhanh - Tin nổi bật - Cổng thông tin Bộ Y tế. https://moh.gov.vn/tin-noi-bat/-/asset_publisher/3Yst7YhbkA5j/content/viet-nam-hien-ty-le-nguoi-mac-benh-ai-thao-uong-ang-gia-tang-nhanh. Accessed April 11, 2025.
13. Biswas M, Rahaman S, Biswas TK, Haque Z, Ibrahim B. Association of Sex, Age, and Comorbidities with Mortality in COVID-19 Patients: A Systematic Review and Meta-Analysis. Intervirology. December 2020: 1-12. doi:10.1159/000512592.