Efficacy of intralesional Triamcinolone Acetonide injection and pressure therapy in the prevention of auricular keloid recurrence after surgical excision

Nguyen Dinh Quan, Nguyen Canh Tung, Vu Nguyen Binh, Vu Dinh Tam, Nguyen Hong Son, Lê Thanh Hien

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Abstract

A controlled pre-post interventional study was conducted on 50 auricular keloids in 41 patients to compare the efficacy of postoperative prophylaxis using intralesional Triamcinolone Acetonide (TAC) injections (26 keloids) – Group 1 versus pressure therapy (24 keloids) – Group 2. Treatment outcomes were assessed using the Kyoto Scar Scale (KSS) at 3 and 6 months postoperatively, with response categorized into four levels: “Very good,” “Good,” “Moderate,” and “Poor,” where “Poor” indicated recurrence. The recurrence rate in Group 1 was 19.2%, significantly lower than 66.7% in Group 2 (p < 0.01). The reduction in KSS score in group 1 was 3.0 [3.0 – 4.0] points, which was greater than that in group 2 at 0.5 [-1.0 – 4.0] points (p < 0.01). These findings suggest that intralesional TAC injection is more effective than pressure therapy in preventing postoperative recurrence of auricular keloids. Recurrent auricular keloids after surgery may be associated with scar location and not related to factors such as age, scar age, or scar area.

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References

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