Kết quả điều trị ung thư phổi không tế bào nhỏ giai đoạn iii bằng hóa xạ trị đồng thời với kỹ thuật xạ trị điều biến liều theo thể tích hình cung (vmat)

Abstract

Volumetric Modulated Arc Therapy – VMAT is an advanced technique which is applied widely among countries by the availability of multileaf collimators (MLC). With VMAT technique, series of small field shapes are created from each beam gantry. The relative weight of the dosage in each projection element will be optimized on each beam gantry. To perform this set up, we utilized directly the optimization of collimator aperture. The study aimed to assess the results and side effects of concurrent chemoradiation therapy by VMAT for treatment of non-small cell lung cancer stage III at K hospital. From June, 2017, we have implemented this technique to treat 30 NSCLC patients. The results showed that the VMAT dose-modulated radiotherapy technique had advantages over the 3D radiotherapy technique in the treatment plan as shown by the indexes of HI, CI, UI, V95 at PTV; V105, volume of organs receiving radiation dose; partial response rate accounted for 80%; The overall 24-month survival rate was 64%, and the rates of early and late complications including pneumonia and esophagitis were low and only at level 1 or 2.