61. Chất lượng cuộc sống và mối liên quan với tình trạng dinh dưỡng ở người bệnh lao kháng Rifampicin/đa kháng thuốc được điều trị phác đồ ngắn hạn tại Việt Nam

Abstract

Tuberculosis (TB) remains a major global public health challenge, particularly in Rifampicin-resistant TB and multidrug-resistant TB (RR/MDR-TB) patients. This study aimed to assess the quality of life and its association with nutritional status, as determined by body mass index (BMI), in patients with RR/MDR-TB who received short-course treatment regimens in Vietnam. A descriptive, retrospective study was conducted on 521 TB patients diagnosed with RR/MDR-TB who underwent a short-course treatment at 35 healthcare facilities within the Drug-Resistant Tuberculosis Management Program across seven provinces in Vietnam. The distribution of quality-of-life levels was as follows: 36.42%, 28.90%, and 34.68% of patients reported “well below,” “below,” and “same or better” in physical health quality (PCS), respectively, while 73.03%, 15.03%, and 11.95% reported “well below,” “below,” and “same or better” in mental health quality (MCS), respectively. Among underweight and malnourished patients (BMI < 18.5), 97.9% experienced a "well below" or "below" quality of life. Similarly, 100% of overweight and obese patients (BMI ≥ 25) reported a "well below" or "below" quality of life. The overweight/obese group exhibited a significant decline in quality of life across most domains, particularly in psychological and social aspects. These findings highlight the need to integrate both physical and mental health support into RR/MDR-TB treatment, with an emphasis on early screening and intervention for psychological conditions to reduce disease burden and enhance treatment outcomes.