67. Tình trạng dinh dưỡng, tăng trưởng và một số yếu tố liên quan ở trẻ thiếu hụt hormone tăng trưởng tại Bệnh viện Nhi Trung ương

Abstract

Growth Hormone Deficiency (GHD) is one of the leading causes of growth retardation in children. A cross-sectional descriptive study was conducted on 62 pediatric patients aged 5 to 15 years old treated at the Center for Endocrinology, Metabolism, Genetics and Molecular Therapy, National Children’s Hospital, from June 2024 to May 2025, to assess nutritional status and related factors. The mean age of participants was 9.38 ± 2.65 years old, the where 58.1% were between 5-10 years old The male-to-female ratio was 1.21:1. Nutritional status was recorded as follows: 58.1% were underweight, 72.6% had stunting, 25.9% had wasting, and 14.5% were overweight/obesity. Notably, 45.2% of children were classified as severely stunted. After 3 months of growth hormone therapy, there was a significant improvement in anthropometric indices. The average height increased by 1.65 ± 1.84cm (p < 0.001), weight increased by 1.02 ± 1.00kg (p < 0.001), and BMI increased slightly by 0.30 ± 0.64 (p < 0.001). No statistically significant association was found between types of malnutrition and variables such as age, gender, birth status, birth weight, or the degree of growth hormone deficiency.