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Published: 2021-02-26
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DOI: https://doi.org/10.52852/tcncyh.v137i1.43
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Vol. 137 No. 1 (2021)
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Thơ, P. K. A. ., Tùng, L. Đình ., & Bình , N. T. . (2021). Clinical characterization and repetitive nerve stimulation test in patients with myasthenia gravis. Journal of Medical Research, 137(1), 213-221. https://doi.org/10.52852/tcncyh.v137i1.43

Clinical characterization and repetitive nerve stimulation test in patients with myasthenia gravis

Pham Kieu Anh Tho, Le Dinh Tung, Nguyen Thanh Binh

Main Article Content

Abstract

The purpose of this study is to describe the clinical characterization and repetitive nerve stimulation test performed in 30 myasthenic patients by a descriptive research method. The research results noted: the average age was 48.57 years old, the female/male ratio was 2:1; there were 7 patients in group I (23.3%), 7 patients in group IIa (23.3%), 7 patients in group IIb (23.3%), 6 patients in group IIIa (20%), 2 patients in group IIIb (6.7%) and 1 patient in group IVa (3.3%); 73.3% of patients had positive AchRs antibodies, 20% of them have thymoma. Repetitive nerve stimulation test (RNS) was positive in 21 patients (70%), patients with affected ocular muscles only (group I) had a positive RNS test rate of 42.9%, and patients with affected limbs and truncal muscles (groups a: IIa, IIIa, IVa) had a positive RNS test rate of 64.2%, The myasthenic patients with affected respiratory and pharyngeal muscle (groups b: IIb, IIIb) had a 100% positive RNS test rate. In conclusion, there is a statistically significant association between the abnormal result on repetitive nerve stimulation test and the myasthenia gravis classification in clinical settings according to MGFA (p = 0.01) and the AchRs antibody quantitative assay (p = 0.001).

Article Details

Keywords

Myasthenia Gravis, repetitive nerve stimulation test

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