Esophageal squamous cell carcinoma presenting as a submuscosal tumor: A case report and literature review
Main Article Content
Abstract
Esophageal submucosal tumors are tumors of mesenchymal origin and are usually benign. These tumors include leiomyomas, stromal tumors, fibromas, and lipomas covered by normal mucosa and are often detected during esophagogastric endoscopy. Esophageal carcinoma presenting as a submucosal tumor is very rare. We report a case of esophageal squamous cell carcinoma presenting clinically and paraclinically as a submucosal tumor. Through this clinical case, we review clinical, paraclinical, and medical reports worldwide.
Article Details
Keywords
Esophageal cancer, esophageal submucosal tumor
References
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2. Morgan E, Soerjomataram I, Rumgay H, et al. The Global Landscape of Esophageal Squamous Cell Carcinoma and Esophageal Adenocarcinoma Incidence and Mortality in 2020 and Projections to 2040: New Estimates From GLOBOCAN 2020. Gastroenterology. 2022; 163(3): 649-658.e642.
3. Rustgi AK, El-Serag HB. Esophageal carcinoma. N Engl J Med. 2014; 371(26): 2499-2509.
4. Schneider MA, Vetter D, Gutschow CA. Management of subepithelial esophageal tumors. Innov Surg Sci. 2025; 10(1): 21-30.
5. Liu ZJ, Sun SY, Guo JT, et al. A primary esophageal mucoepidermoid carcinoma mimicking a benign submucosal tumor. Dis Esophagus. 2012; 25(2): 178-179.
6. Sonthalia N, Jain SS, Surude RG, Pawar VB, Udgirkar S, Rathi PM. Primary Esophageal Intramural Squamous Cell Carcinoma Masquerading as a Submucosal Tumor: A Rare Presentation of a Common Disease. Clin Med Insights Gastroenterol. 2016; 9: 63-66.
7. Wang W, Li D, Zheng L, Zhan H. Oesophageal squamous cell carcinoma mimicking submucosal tumour. BMC Gastroenterol. 2021; 21(1): 150.
8. Li Z, Seah TE, Tang P, Ilankovan V. Incidence of second primary tumours in patients with squamous cell carcinoma of the tongue. Br J Oral Maxillofac Surg. 2011; 49(1): 50-52.
9. Lee KD, Lu CH, Chen PT, et al. The incidence and risk of developing a second primary esophageal cancer in patients with oral and pharyngeal carcinoma: a population-based study in Taiwan over a 25 year period. BMC Cancer. 2009; 9: 373.