Tình hình thiếu cơ và một số yếu tố liên quan ở bệnh nhân bệnh thận mạn chưa lọc máu giai đoạn 3 – 4 tại Bệnh viện Vạn Hạnh

Abstract

Sarcopenia is a common complication in patients with non–dialysis-dependent chronic kidney disease (CKD), contributing to an increased risk of adverse clinical outcomes; however, it remains underrecognized in routine clinical practice. Moreover, data regarding its prevalence and independently associated factors in Vietnam are still limited. As such, we conducted a cross-sectional study involving 70 patients with stage 3–4 CKD at Van Hanh Hospital to gather further data on the prevalence of sarcopenia in vietnamese patients. Sarcopenia was diagnosed according to the 2019 Asian Working Group for Sarcopenia (AWGS) criteria, based on muscle mass measured by dual-energy X-ray absorptiometry (DXA), handgrip strength, and gait speed. The overall prevalence of sarcopenia was 15.7%, with severe sarcopenia accounting for 4.3%. Reduced muscle strength was the most frequent component (47.1%), followed by impaired physical performance (25.7%) and low muscle mass (22.9%). Multivariable analysis identified male gender, prolonged corticosteroid use, and diabetes mellitus as independent factors associated with sarcopenia (p < 0.05). In conclusion, initial study findings suggest that sarcopenia is relatively prevalent among patients with non–dialysis-dependent CKD stages 3–4. Effective screening strategies and early management should therefore be implemented, especially among patients with multiple risk factors.