Association between Helicobacter pylori infection and irritable bowel syndrome according to the ROME IV criteria
Main Article Content
Abstract
Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder that significantly affects patients’ quality of life; however, the role of Helicobacter pylori infection in the pathogenesis of IBS remains controversial. A case–control study was conducted on 220 patients with gastrointestinal symptoms who underwent upper gastrointestinal endoscopy and colonoscopy at Can Tho University of Medicine and Pharmacy Hospital, including 110 patients with IBS and 110 non-IBS controls, to determine the association between Helicobacter pylori infection and IBS according to Rome IV criteria. Helicobacter pylori infection was identified using the urease test from gastric mucosal biopsy specimens. The prevalence of Helicobacter pylori infection was higher in the IBS group than in the non-IBS group (61.4% vs. 38.6%, p = 0.008). Multivariate logistic regression analysis showed that Helicobacter pylori infection was independently associated with IBS (adjusted OR = 2.13; 95% CI: 1.18 – 3.85; p = 0.01). Helicobacter pylori infection was significantly associated with irritable bowel syndrome according to Rome IV criteria.
Article Details
Keywords
Irritable Bowel Syndrome, Helicobacter pylori, ROME IV
References
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