Article Sidebar

PDF (Tiếng Việt)
Published: 2021-12-01
Abstract Views: 849
Views PDF (Tiếng Việt): 703
DOI: https://doi.org/10.52852/tcncyh.v147i11.503
Issue
Vol. 147 No. 11 (2021)
Section
Các bài báo
How to Cite
Mai, H. T. N. ., Khuy, Đoàn M. ., Minh, T. N. ., & Mạnh, P. T. . (2021). Spindle cell breast carcinoma: a rare case report. Journal of Medical Research, 147(11), 267-272. https://doi.org/10.52852/tcncyh.v147i11.503

Spindle cell breast carcinoma: a rare case report

Thị Ngọc Mai, Đoàn Minh Khuy, Trần Ngọc Minh, Phạm Thuần Mạnh

Main Article Content

Abstract

Spindle cell carcinoma is a rare variant of breast cancer which has been classified under the broad rubric of metaplastic carcinoma. Neoplasm characterized by differentiation of mesenchymal-looking elements and/or the epithelial structure, mimicking a sarcoma. Its prognosis remains poor, with a high rate of local recurrence and distant metastasis. We report a case of a 61-year-old woman who consulted our institution following palpation of a nodule of the left breast. The patient was diagnosed with spindle cell carcinoma of the breast. The diagnosis was based primarily on histological and immunohistochemical studies.

Article Details

Keywords

carcinoma, spindle cell, breast.

References

1. Tan PH, Ellis I, Allison K, et al. The 2019 World Health Organization classification of tumours of the breast. Histopathology. 2020; 77(2):181-185. doi:10.1111/his.14091.
2. Moten AS, Jayarajan SN, Willis AI. Spindle cell carcinoma of the breast: a comprehensive analysis. The American Journal of Surgery. 2016;211(4):716-721. doi:10.1016/j.amjsurg.2015.11.023.
3. Alaoui M’hamdi H, Abbad F, Rais H, et al. Rare variant of metaplastic carcinoma of the breast: a case report and review of the literature. Journal of Medical Case Reports. 2018;12(1):43. doi:10.1186/s13256-017-1553-3
4. Amy E McCart Reed, Emarene M Kalaw, Sunil R Lakhani. An Update on the Molecular Pathology of Metaplastic Breast Cancer. Breast Cancer: Targets and Therapy. 2021;13:161-170. doi:10.2147/bctt.s296784.
5. Choi BB, Shu KS. Metaplastic carcinoma of the breast: multimodality imaging and histopathologic assessment. Acta Radiol. 2012;53(1):5-11. doi:10.1258/ar.2011.110341.
6. Rungta S, Kleer CG. Metaplastic carcinomas of the breast: Diagnostic challenges and new translational insights. Arch Pathol Lab Med. 2012;136(8):896-900. doi:10.5858/arpa.2012-0166-CR.
7. Reis-Filho JS, Gobbi H, Mccart Peed AE. Metaplastic carcinoma. In: WHO Classification of Breast Tumours. 5th ed. Lyon: IARC; 2019:134-138.
8. McMullen ER, Zoumberos NA, Kleer CG. Metaplastic Breast Carcinoma: Update on Histopathology and Molecular Alterations. Arch Pathol Lab Med. 2019;143(12):1492-1496. doi:10.5858/arpa.2019-0396-RA
9. Carter MR, Hornick JL, Lester S, Fletcher CDM. Spindle Cell (Sarcomatoid) Carcinoma of the Breast: A Clinicopathologic and Immunohistochemical Analysis of 29 Cases. The American Journal of Surgical Pathology. 2006; 30(3):300-309. doi:10.1097/01.pas.0000184809.27735.a1
10. Luini A, Aguilar M, Gatti G, et al. Metaplastic carcinoma of the breast, an unusual disease with worse prognosis: the experience of the European Institute of Oncology and review of the literature. Breast Cancer Res Treat. 2007;101(3):349-353. doi:10.1007/s10549-006-9301-1