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Published: 2026-08-04
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DOI: https://doi.org/10.52852/tcncyh.v204i7.5191
Issue
Vol. 204 No. 7 (2026)
Section
Các bài báo
How to Cite
Thâm, T. D., Thành, C. N., Đang, C. H., & Nga, T. K. (2026). Factors associated with day-5 embryo culture outcomes in infertile women with polycystic ovary syndrome . Journal of Medical Research, 204(7), 136-146. https://doi.org/10.52852/tcncyh.v204i7.5191

Factors associated with day-5 embryo culture outcomes in infertile women with polycystic ovary syndrome

Tran Duy Tham, Cao Ngoc Thanh, Chau Huu Dang, Tran Khanh Nga

Main Article Content

Abstract

A descriptive cross-sectional study was conducted among 61 infertile women with polycystic ovary syndrome (PCOS) at Can Tho City Obstetrics and Gynecology Hospital from July 2024 to February 2026. The study aimed to describe clinical and laboratory characteristics, day-5 embryo culture outcomes and selected associated factors. Primary infertility accounted for 73.8% of cases, and phenotype D was the most common phenotype, accounting for 50.8%. The mean BMI was 22.9 ± 3.0 kg/m². The median number of retrieved oocytes was 18.0. The mean number of normally fertilized two-pronuclear (2PN) zygotes was 15.1 ± 8.0, the mean number of good-quality day-5 blastocysts was 6.6 ± 5.2 and the proportion of good-quality day-5 blastocysts relative to the number of 2PN zygotes was 42.0 ± 26.8%. In the quasi-binomial regression model, BMI was inversely associated with the proportion of good-quality day-5 blastocysts relative to the number of 2PN zygotes after multivariable adjustment, with an OR of 0.83 (95% CI: 0.75 – 0.91; p < 0.001). These preliminary findings suggest that BMI may be associated with day-5 blastocyst culture outcomes in infertile women with PCOS.

Article Details

Keywords

Polycystic ovary syndrome, in vitro fertilization, day-5 embryo

References

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