Anti-fatigue effects of Nhat Bao Nutritional Milk in experimental animals
Main Article Content
Abstract
This study aimed to evaluate the anti-fatigue effects of Nhat Bao Nutritional Milk (CSTD) in experimental animals. Fatigue was induced in Swiss mice by daily swimming and Rotarod testing for one week. Subsequently, the mice were orally administered distilled water, sulbutiamine at 96 mg/kg/day, or CSTD at 15.6 or 31.2 g/kg/day for 4 consecutive weeks. The anti-fatigue effects of CSTD were assessed through a rotarod performance test, a grip strength test, a forced swimming test, and the determination of biochemical parameters. CSTD at 15.6 g/kg/day showed a trend toward increased body weight, prolonged Rotarod performance time, extended swimming time, and increased grip strength compared to the model group; however, these differences were not statistically significant. In contrast, CSTD at 31.2 g/kg/day significantly increased body weight, prolonged Rotarod and swimming times, and enhanced grip strength compared to the model group. Additionally, this dose increased blood glucose levels and reduced serum AST, ALT, and BUN levels. These findings suggest that CSTD at 31.2 g/kg/day exerts significant anti-fatigue effects in experimental animals.
Article Details
Keywords
Nhat Bao Nutritional Milk, anti-fatigue, Swiss mice
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