The clinical value of several reticulocyte indice

Thanh Nga Phạm Thị, Nguyễn Quang Tùng, Nguyễn Chí Thành

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Abstract

Reticulocytes are immature red blood cells. Reticulocytes originate in the bone marrow and undergo further diferentiation into mature red blood cells. Then, they are released into the peripheral. The enumeration of peripheral blood reticulocytes (“reticulocyte counting”) and rate of reticulocyte are often performed to obtain information about the function of the erythropoiesis. Reticulocyte enumeration is also valued in monitoring bone marrow regenerative activity after chemotherapy or bone marrow transplantation. Currently, the new techniques provide a variety of reticulocyte-related parameters, such as reticulocyte hemoglobin content (CHr), Immature reticulocyte fraction (IRF), reticulocyte hemoglobin (retHb), reticulocyte maturation index (RMI). These parameters are under evaluation in the clinical diagnosis and monitoring of hematologic pathology.

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References

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