Preliminary assessment of cerebral dural venous sinus variants on MRI in patients with chronic headache

Nguyen Hong Phuc, Pham Hong Duc

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Abstract

This retrospective cross-sectional study preliminarily described the clinical characteristics, brain MRI findings, and distribution of cerebral dural venous sinus variants on contrast-enhanced MRI/MR venography in adults with chronic headache. Thirty-seven patients aged 18 years or older who underwent contrast-enhanced imaging for clinical diagnostic purposes at Viet Tiep Friendship Hospital, Hai Phong, from January 2025 to January 2026 were included. Mean age was 55.19 ± 15.61 years old and 64.9% were female. Dizziness was the most common accompanying symptom (32.4%), followed by nausea and vomiting (18.9% each). No clinically meaningful intracranial abnormality was identified on routine brain MRI in 59.5% of cases; paranasal sinusitis accounted for 16.2%, while brain tumors and intracranial hemorrhage each accounted for 8.1%. Left transverse sinus hypoplasia and left sigmoid sinus hypoplasia were the most frequent variants (59.5% each). Bilateral symmetry of the transverse and sigmoid sinuses was present in 21.6% and 27.0% of patients, respectively, and type IB was the most common configuration (29.7%). These findings reflect a selected single-center clinical cohort undergoing contrast-enhanced MRI/MRV and mainly support image interpretation by improving differentiation between anatomical variants and venous occlusive disease rather than implying a causal relationship with chronic headache.

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