Article Sidebar

PDF (Tiếng Việt)
Published: 2026-08-04
Abstract Views: 0
Views PDF (Tiếng Việt): 0
DOI: https://doi.org/10.52852/tcncyh.v204i7.5311
Issue
Vol. 204 No. 7 (2026)
Section
Các bài báo
How to Cite
Khải, T. Q., Công, T. C., Tuyền, N. N., Hương, P. N. Q., & Nghĩa, D. H. (2026). Comparison of effectiveness of nasal intermittent positive pressure ventilation (NIPPV) and nasal continuous positive airway pressure (NCPAP) within the first 24 hours of treatment in preterm infants with respiratory distress syndrome at Vinh Long General hospital, 2025-2026. Journal of Medical Research, 204(7), 242-251. https://doi.org/10.52852/tcncyh.v204i7.5311

Comparison of effectiveness of nasal intermittent positive pressure ventilation (NIPPV) and nasal continuous positive airway pressure (NCPAP) within the first 24 hours of treatment in preterm infants with respiratory distress syndrome at Vinh Long General hospital, 2025-2026

Tran Quang Khai, Tran Chi Cong, Nguyen Ngoc Tuyen, Phan Ngoc Que Huong, Duong Huu Nghia

Main Article Content

Abstract

This matched prospective cohort study was conducted on 76 preterm infants with respiratory distress syndrome (RDS) at Vinh Long General Hospital (05/2025–04/2026) to describe clinical and paraclinical characteristics and to compare treatment outcomes within the first 24 hours after intervention between nasal intermittent positive pressure ventilation (NIPPV) and nasal continuous positive airway pressure (NCPAP). The most common clinical signs were chest retractions (96.1%), grunting (73.7%), and tachypnea (72.4%); respiratory acidosis occurred in 71.6% of cases. At 1 hour, the NIPPV group showed significantly greater improvement in lethargy, chest retractions, and tachypnea (p < 0.05). At 24 hours, the respiratory support failure rate in the NCPAP group was significantly higher than in the NIPPV group (28.9% vs. 5.3%, p = 0.006). Thus, NIPPV appeared to be more effective than NCPAP in providing early symptom improvement and reducing respiratory support failure within the first 24 hours in preterm infants with RDS.

Article Details

Keywords

NIPPV, NCPAP, preterm infants, respiratory distress syndrome (RDS), treatment

References

1. Tochie JN, Sibetcheu AT, Arrey-Ebot PE, Choukem SP. Global, Regional and National Trends in the Burden of Neonatal Respiratory Failure and essentials of its diagnosis and management from 1992 to 2022: a scoping review. Eur J Pediatr. Jan 2024; 183(1): 9-50. doi:10.1007/s00431-023-05238-z.
2. Farhat A, Saeidi R, Zegheibizadeh F, Golhasani F, Mohammadzadeh A. Causes of Death and the Mortality Rate of Newborns in NICU in Mashhad for Five Years. Iranian Journal of Neonatology. 2022; 13(3).
3. Chirculescu R, Balanescu PC, Peltecu G. Distal pulmonary epithelial maturation in preterm infants: does the lung of the preterm infant continue its functional pulmonary development postnatally? J Med Life. May 2025; 18(5): 478-486. doi:10.25122/jml-2025-0072.
4. Dursun M, Uslu S, Bulbul A, Celik M, Zubarioglu U, Bas EK. Comparison of early nasal intermittent positive pressure ventilation and nasal continuous positive airway pressure in preterm infants with respiratory distress syndrome. Journal of tropical pediatrics. 2019; 65(4): 352-360.
5. Ahmed SH, Razzaq A, Ijaz W, Saleem S, Jabeen M. Comparison of short-term outcomes between Nasal Continuous Positive Airway Pressure and Nasal Intermittent Positive Pressure Ventilation in preterm neonates with respiratory distress syndrome. The Professional Medical Journal. 2024; 31(12): 1650-1656.
6. Lemyre B, Deguise MO, Benson P, Kirpalani H, Ekhaguere OA, Davis PG. Early nasal intermittent positive pressure ventilation (NIPPV) versus early nasal continuous positive airway pressure (NCPAP) for preterm infants. Cochrane Database of Systematic Reviews. 2023; (7). doi:10.1002/14651858.CD005384.pub3.
7. Bộ Y tế. Quyết định số 2323/QĐ-BYT của Bộ Y tế ngày 14/7/2025 ban hành tài liệu chuyên môn “Hướng dẫn quốc gia về các dịch vụ chăm sóc và điều trị trẻ sơ sinh” (2025).
8. Kumar J, Kumar P, Bhandari V. Noninvasive Ventilation Strategies in Neonates. Indian Pediatrics. 2025/06/01 2025; 62(6): 451-460. doi:10.1007/s13312-025-00077-7.
9. Mahmoud RA, Schmalisch G, Oswal A, Christoph Roehr C. Non-invasive ventilatory support in neonates: An evidence-based update. Paediatr Respir Rev. Dec 2022; 44:11-18. doi:10.1016/j.prrv.2022.09.001.
10. Nguyễn Thị Thanh Bình, Hoàng Mai Linh, Nguyễn Nồm, Nguyễn Thị Thảo Nhi, Trần Kiêm Hảo. Kết quả điều trị và một số yếu tố liên quan đến hội chứng suy hô hấp sơ sinh ở trẻ non tháng. Tạp chí Nghiên cứu Y học. 03/26 2025; 188(3): 199-208. doi:10.52852/tcncyh.v188i3.3157.
11. Nguyễn Phan Trọng Hiếu, Trần Chí Thiện, Nguyễn Thành Nam. Đánh giá kết quả điều trị suy hô hấp sơ sinh và một số yếu tố liên quan. Tạp chí Y học Việt Nam. 06/22 2022; 515(1)doi:10.51298/vmj.v515i1.2680.