Đặc điểm lâm sàng, cận lâm sàng và kết quả bước đầu của phương pháp phẫu thuật cắt tuyến ức nội soi một lỗ dưới mũi ức điều trị nhược cơ tại Bệnh viện Bạch Mai giai đoạn 2023 - 2025

Abstract

This study included 51 patients with myasthenia gravis who underwent uniportal subxiphoid thoracoscopic thymectomy at the Department of Thoracic Surgery, Bach Mai Hospital between 2023 and 2025 to evaluate clinical characteristics, paraclinical characteristics and preliminary surgical outcomes. The mean age was 46.45 ± 15.21 years old, 70.59 % females. The most common symptom was ptosis (78.43%), followed by muscle weakness/fatigue (33.33%) and dysphagia (23.53%). All patients received stable medical treatment before surgery and were mainly classified as Osserman stage I–II. Imaging findings showed that most tumor lesions were well-defined, contrast-enhanced, and homogeneous. Histopathological examination revealed 72.55% of thymoma and 27.45% of thymic hyperplasia. The mean operative time was 107.15 ± 22.78 minutes, with no conversion to open surgery. The mean postoperative hospital stay was 4.90 ± 3.98 days, and postoperative complications were uncommon. Uniportal subxiphoid thoracoscopic thymectomy appears to be a safe, minimally invasive, and feasible approach for the treatment of myasthenia gravis.