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Published: 2021-12-01
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DOI: https://doi.org/10.52852/tcncyh.v147i11.538
Issue
Vol. 147 No. 11 (2021)
Section
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How to Cite
Hoa, T. T. ., Luận, Đào T. ., Dũng, T. N., & Quỳnh, N. T. . (2021). Colorectal adenomacarcinoma in a patient with peutz-jeghers syndrome. Journal of Medical Research, 147(11), 296-301. https://doi.org/10.52852/tcncyh.v147i11.538

Colorectal adenomacarcinoma in a patient with peutz-jeghers syndrome

Hoa1, Đào Thị Luận, Trần Ngọc Dũng, Nguyễn Thị Quỳnh
1 Đại học y Hà Nội

Main Article Content

Abstract

Peutz-Jeghers Syndrome (PJS) is a rare disease, characterized by hamartomatous polyposis of the gastro-intestinal (GI) tract and pigmentation around lips, eyelids and macules on the buccal mucosa. The objective of the study was to describe one case of colorectal adenocarcinoma in a patient with Peutz-Jeghers Syndrome. A case study report was applied. A 36-year-old male with PJS was hospitalized because of vomiting and intermittent abdominal pain. Imaging showed small-bowel intussusception in the pelvic region, along with colorectal polyps; the largest polyp in the high rectum measuring 38 x 37 mm was lobulated. Pathological results showed that the large polyp in the rectum is adenocarcinoma invading the smooth muscle layer; other polyps are typical Peutz-Jeghers polyps, with low-grade dysplasia. The patient was diagnosed with a moderately differentiated adenocarcinoma invading the smooth muscle layer/ Peutz-Jeghers syndrome.

Article Details

Keywords

Peutz-Jeghers Syndrome, colorectal adenocarcinoma.

References

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