Clinical, subclinical characteristics and results of treatment of pediatric acute pancreatitis at Can Tho Children’s hospital
Main Article Content
Abstract
Acute pancreatitis is an acute inflammatory condition of the pancreas characterized by diverse clinical manifestations and the potential for severe disease progression. This cross-sectional descriptive study enrolled 61 children diagnosed with acute pancreatitis at Can Tho Children's Hospital between June 2024 and May 2026. 67% of the study population included children older than 10 years old. Abdominal pain (96.7%) and vomiting (75.4%) were common in all patients, while fever was more frequently observed in patients with moderately severe–severe acute pancreatitis. White blood cell count, neutrophil percentage, and C-reactive protein levels were significantly higher in the moderately severe–severe group than the mild group. The mean length of hospital stay was 9.8 ± 3.3 days. Patients with moderately severe–severe acute pancreatitis had longer fasting periods and higher fluid requirements compared to patients with mild disease. These findings indicate that abdominal pain and vomiting are the predominant clinical manifestations of pediatric acute pancreatitis, while elevated white blood cell count, neutrophil percentage, and C-reactive protein levels are associated with greater disease severity.
Article Details
Keywords
Acute pancreatitis, clinical, paraclinical, children
References
2. Lautz TB, Chin AC, Radhakrishnan J. Acute pancreatitis in children: spectrum of disease and predictors of severity. J Pediatr Surg. 2011; 46(6): 1144-1149. doi:10.1016/j.jpedsurg.2011.03.044.
3. Abu-El-Haija M, Kumar S, Quiros JA, et al. Management of acute pancreatitis in the pediatric population: a clinical report from the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Pancreas Committee. J Pediatr Gastroenterol Nutr. 2018; 66(1): 159-176. doi:10.1097/MPG.0000000000001715.
4. Phạm Thị Quỳnh. Đặc điểm lâm sàng, cận lâm sàng viêm tụy cấp ở trẻ em tại Bệnh viện Nhi Thanh Hóa. Tạp chí Y học Việt Nam. 2025; 557(1): 140-144. doi:10.51298/vmj.v557i1.16585.
5. World Health Organization. WHO Child Growth Standards: Length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: Methods and development. Geneva: World Health Organization; 2006.
6. Calihan J. Cardiology. In: Tschudy MM, Arcara KM, eds. The Harriet Lane Handbook. 22nd ed. Philadelphia, PA: Elsevier; 2020: 145-188.
7. Nguyễn Hoài Thương, Ninh Quốc Đạt, Nguyễn Thị Việt Hà. Coagulation disorders in children with acute pancreatitis at the Vietnam National Children’s Hospital. Tạp chí Nghiên cứu Y học. 2023; 173(12E13): 112-119. doi:10.52852/tcncyh.v173i12E13.1711.
8. Deveci U, Unsal SK, Dogan Y. A retrospective review of children followed up with the diagnosis of acute pancreatitis. Niger J Clin Pract. 2023; 26(12): 1876-1885. doi:10.4103/njcp.njcp_441_23.
9. Bùi Thị Thu Hường. Nghiên cứu đặc điểm lâm sàng và cận lâm sàng bệnh viêm tụy cấp ở trẻ em tại Bệnh viện Nhi Trung ương. Luận văn thạc sĩ. Hà Nội: Trường Đại học Y Hà Nội; 2015.
10. Chu Thị Phương Mai, Đỗ Thị Minh Phương, Nguyễn Thị Việt Hà. Kết quả điều trị bệnh viêm tụy cấp ở trẻ em tại Bệnh viện Nhi Trung ương. Tạp chí Y học Việt Nam. 2020; 490(3): 109-112. doi.org/10.51298/vmj.v554i1.15542.
11. Jaday SJ, Shah H. A randomized study of outcome of acute pancreatitis in tertiary care hospital Gujarat, India. Int Surg J. 2018; 5(6): 2268-2274. doi:10.18203/2349-2902.isj20182235.
12. Trần Đình Huy, Võ Thị Mỹ Dung. Hồi sức dịch truyền trong viêm tụy cấp: từ chiến lược bù dịch tích cực sang cá thể hóa. Tạp chí Y học TP. Hồ Chí Minh. 2026; 29(3). doi:10.32895/hcjm.m.2026.03.01.
13. Suzuki M, Saito N, Naritaka N, et al. Scoring system for the prediction of severe acute pancreatitis in children. Pediatr Int. 2015; 57(1): 113-118. doi:10.1111/ped.12449.
14. Orkin SH, Trout AT, Fei L, et al. Sensitivity of biochemical and imaging findings for the diagnosis of acute pancreatitis in children. J Pediatr. 2019; 213:143-148.e2. doi:10.1016/j.jpeds.2019.06.028.
15. Norris N, Guimaraes AR, Freeman AJ, et al. Liberal fluid resuscitation is associated with improved outcomes in pediatric acute pancreatitis. J Pediatr. 2025; 276: 114329. doi:10.1016/j.jpeds.2024.114329.