Clinical characteristics and etiologies of uveitis at Hanoi Medical University Hospital
Main Article Content
Abstract
Uveitis is a major cause of visual impairment with diverse clinical manifestations and etiologies. This study aimed to describe the clinical characteristics and causes of uveitis in patients at Hanoi Medical University Hospital. A cross-sectional study was conducted on 90 patients diagnosed with uveitis at the Department of Ophthalmology during 2023 – 2024. Uveitis was most common in the working-age group (82.2%) and in females (60.4%). Bilateral involvement accounted for 61.1% of cases. Panuveitis was the most common anatomical type (35.6%), followed by anterior uveitis (32.2%). Blurred vision was the most frequent symptom (84.6%), while ocular pain, red eye, and floaters were reported in 49.5%, 38.5%, and 16.5% of patients, respectively. 48.9% of patents were diagnosed with Idiopathic uveitis. Among infectious causes, Toxocara-associated uveitis was the most common, whereas Vogt–Koyanagi–Harada syndrome was the leading noninfectious etiology. Comprehensive evaluation of clinical manifestations and etiologies is important for accurate diagnosis, early treatment, prevention of complications, and preservation of visual function.
Article Details
Keywords
Uveitis, clinical characteristics, etiology
References
2. Deschenes J, Murray PI, Rao NA, Nussenblatt RB. International Uveitis Study Group (IUSG): clinical classification of uveitis. Ocul Immunol Inflamm. 2008;16(1):1-2. doi:10.1080/09273940801899822
3. Jabs DA, Nussenblatt RB, Rosenbaum JT; Standardization of Uveitis Nomenclature (SUN) Working Group. Standardization of uveitis nomenclature for reporting clinical data: results of the First International Workshop. Am J Ophthalmol. 2005;140(3):509-516. doi:10.1016/j.ajo.2005.03.057
4. Acharya NR, Tham VM, Esterberg E, et al. Incidence and prevalence of uveitis: results from the Pacific Ocular Inflammation Study. JAMA Ophthalmol. 2013;131(11):1405-1412. doi:10.1001/jamaophthalmol.2013.4237
5. Rao NA. Uveitis in developing countries. Indian J Ophthalmol. 2013;61(6):253-254. doi:10.4103/0301-4738.114090
6. Nguyen M, Siak J, Chee SP, Diem VQH. The spectrum of uveitis in Southern Vietnam. Ocul Immunol Inflamm. 2017;25(suppl 1):S100-S106. doi:10.1080/09273948.2016.1231826
7. Sève P, Cacoub P, Bodaghi B, et al. Uveitis: Diagnostic work-up. A literature review and recommendations from an expert committee. Autoimmun Rev. 2017;16(12):1254-1264.
8. Classification Criteria for Sarcoidosis-Associated Uveitis. Am J Ophthalmol. 2021;228:220-230.
9. Rathinam SR, Babu M. Algorithmic approach in the diagnosis of uveitis. Indian J Ophthalmol. 2013;61(6):255-262.
10. Ramanan AV, Dick AD, Benton D, et al. A randomised controlled trial of the clinical effectiveness, safety and cost-effectiveness of adalimumab in combination with methotrexate for the treatment of juvenile idiopathic arthritis associated uveitis (SYCAMORE Trial). Trials. 2014;15:14.
11. Rajan RS, Mohamed SO, Salowi MA, et al. Demography and clinical pattern of newly diagnosed uveitis patients in Malaysia. J Ophthalmic Inflamm Infect. 2022;12:28. doi:10.1186/s12348-022-00306-1
12. Hao T, Yang L, Li B, et al. Epidemiology of 2000 Chinese uveitis patients from Northeast China. Br J Ophthalmol. 2021;105:317-321. doi:10.1136/bjophthalmol-2020-316256
13. Grajewski RS, Caramoy A, Frank KF, et al. Spectrum of uveitis in a German tertiary center: review of 474 consecutive patients. Ocul Immunol Inflamm. 2015;23:346-352. doi:10.3109/09273948.2014.1002567
14. Abaño JM, Galvante PR, Siopongco P, et al. Review of epidemiology of uveitis in Asia: pattern of uveitis in a tertiary hospital in the Philippines. Ocul Immunol Inflamm. 2017;25(suppl 1):S75-S80. doi:10.1080/09273948.2017.1335755
15. Tsirouki T, Dastiridou A, Symeonidis C, et al. A focus on the epidemiology of uveitis. Ocul Immunol Inflamm. 2018;26(1):2-16. doi:10.1080/09273948.2016.1196713
16. Akhter M, Toy B. Big data–based epidemiology of uveitis and related intraocular inflammation. Asia Pac J Ophthalmol. 2021;10(1):60. doi:10.1097/APO.0000000000000364
17. Durrani OM, Tehrani NN, Marr JE, Moradi P, Stavrou P, Murray PI. Degree, duration, and causes of visual loss in uveitis. Br J Ophthalmol. 2004;88(9):1159-1162. doi:10.1136/bjo.2003.037226
18. Read RW, Holland GN, Rao NA, et al. Clinical spectrum and management options in Vogt-Koyanagi-Harada disease. Clin Ophthalmol. 2017;11:1179-1192. doi:10.2147/OPTH.S125597