Echocardiographical characteristics and outcomes of transcatheter closure of fenestrated atrial septal defects at Hanoi Medical University Hospital

Nguyen Lan Hiếu, Hoang Van Ky, Ngo Thi Hanh, Le Xuan Hung, Nguyen Thi Minh Ly

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Abstract

Percutaneous closure of fenestrated atrial septal defects (ASD) remains challenging due to difficulties in assessing lesion morphology, device selection, and residual shunting after intervention. We conducted a retrospective case series with short-term follow-up including 31 patients with fenestrated ASD treated at Hanoi Medical University Hospital. The mean age was 34.6 ± 19.7 years old, predominantly females at 74.2%. On transesophageal echocardiography (TEE), the mean number of defects per patient was 2.4 ± 0.5. Compared with transthoracic echocardiography (TTE), TEE detected a significantly higher proportion of patients with ≥ 3 fenestrations and atrial septal aneurysm among the 25 patients, all underwent both TTE and TEE (44% vs. 8% and 52% vs. 28%, respectively; p < 0.05). The mean device size used was 29.9 ± 7.9 mm. The procedural success rate was 96.8%. One case of device embolization occurred and required surgical closure. Residual shunt was observed in 20% of patients. Preliminary findings indicate that percutaneous transcatheter closure of fenestrated ASD is a feasible approach, with favorable immediate and short-term follow-up outcomes.

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References

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