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Published: 2021-12-01
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DOI: https://doi.org/10.52852/tcncyh.v147i11.579
Issue
Vol. 147 No. 11 (2021)
Section
Các bài báo
How to Cite
Nguyễn Thị, N. L., Tạ Thành, V., Đặng Thị, N. D., Vũ Văn, Q., Nguyễn Thùy, L., & Nguyễn Thị, T. L. (2021). Nutritional status and genetic characteristics of gastric cancer patients at four hospitals in Hanoi. Journal of Medical Research, 147(11), 63-71. https://doi.org/10.52852/tcncyh.v147i11.579

Nutritional status and genetic characteristics of gastric cancer patients at four hospitals in Hanoi

Ngọc Lan Nguyễn Thị, Văn Tạ Thành, Ngọc Dung Đặng Thị, Quý Vũ Văn, Linh Nguyễn Thùy, Thu Liễu Nguyễn Thị

Main Article Content

Abstract

Nutritional status in gastric cancer patients is one of the important factors affecting the effectiveness of treatment as well as the patient’s quality of life. A cross-sectional descriptive study was conducted on 302 gastric cancer patients to evaluate nutritional status as well as the relationship between clinical characteristics and genotype to nutritional status in gastric cancer patients. The results of this study showed that the average age of the study participants was 63.55 ± 11.98, the common age group was 60-69, accounting for 33.44%. The male/female ratio in the study was 2.25/1. 143 (47.4%) of gastric cancer patients smoked. 135 (44.7%) of gastric cancer patients consumed alcohol at a risk level. The proportion of patients at risk of moderate and severe malnutrition (PG-SGA B and C) is 39.7%. Regarding the genotypic characteristics, the single nucleotide polymorphism rs4072037 – MUC1 genotype AA accounted for 49.34% while with the single nucleotide polymorphism rs2070803 – MUC1 genotype GG accounted for 45.7%. No statistically significant relationship was found between age, gender, histopathologic type, smoking history, alcohol consumption history and SNPs rs4072037, rs2070803 of MUC1 gene with nutritional status of stomach cancer patients.


 

Article Details

Keywords

Gastric cancer, PG-SGA, MUC1 gene, rs4072037, rs2070803.

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