Image diagnostics and outcome of patients with m2 branch occlusion of middle cerebral artery treated by mechanical thrombectomy

Tran Tat Hien, Nguyen Quang Anh, Tran Anh Tuan

Main Article Content

Abstract

To describe imaging characteristics and results of mechanical thrombectomy in patients with M2 branch occlusion of the middle cerebral artery. This is a cross-sectional study on 38 patients with acute cerebral infarction due to M2 occlusion of the middle cerebral artery from 1/ 2018 to 6/2021 at the Center of Radiology - Bachmai Hospital. CT images revealed early signs of infarction including deletion of the insular band (26.5%), thrombosis increased density 67.6%, scroll groove deletion 44.1% and substance boundary deletion, gray white 47.1%. MRI images revealed 100% increased brain parenchymal signal on DWI, 50% increased vascular signal on FLAIR and 25% of cases increased brain parenchymal signal on FLAIR. The rate of patients with good revascularization after intervention (TICI 2b-3) was 89%. The percentage of patients with a good clinical recovery after three months (mRS =0-2) was 57.89%. Factors of early hospital admission within the first 3 hours and NIHSS scores influence the likelihood of good clinical recovery after 3 months.

Article Details

References

1. Mauro, M.A. Image - guided interventions. Saunders/Elsevier. Published online 2008.
2. Broderick JP. William M. Feinberg Lecture: stroke therapy in the year 2025: burden, breakthroughs, and barriers to progress. Stroke. 2004;35(1):205 - 211. doi:10.1161/01.STR.0000106160.34316.19
3. Hacke W, Kaste M, Bluhmki E, et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med. 2008;359(13):1317 - 1329. doi:10.1056/NEJMoa0804656
4. Koh JS, Lee SJ, Ryu C - W, Kim HS. Safety and efficacy of mechanical thrombectomy with solitaire stent retrieval for acute ischemic stroke: a systematic review. Neurointervention. 2012;7(1):1 - 9. doi:10.5469/neuroint.2012.7.1.1
5. Nogueira RG et al. Trevo versus Merci retrievers for thrombectomy revascularization of large vessel occlusions in acute ischaemic stroke (TREVO 2): a randomised trial. Lancet. 2012;380(9849):1231 - 1240.
6. Saver JL et al. Solitaire flow restoration device versus the Merci retriever in patients with acute ischemic stroke (SWIFT): a randomized, parallel - group, non - inferiority trial. Lancet. 2012;380(9849):1241 - 1249.
7. Mark FB, Barry WC, Michael AP. Neuroscience Exploring the Brain, 3rd Edition. Lippincott Williams & Wilkins; 2007.
8. Vũ Đăng Lưu, Nguyễn Quang Anh. Kết quả của phương pháp lấy huyết khối bằng dụng cụ cơ học stent Solitaire trong điều trị nhồi máu não tối cấp. Tạp Chí Nghiên Cứu Y Học. 2015;(2):33 - 40.
9. Vũ Anh Nhị, Phạm Nguyên Bình. Đánh giá tính an toàn và hiệu quả phương pháp lấy huyết khối bằng dụng cụ cơ học Solitaire ở bệnh nhân đột quỵ thiếu máu não. Tạp Chí Y Học TP Hồ Chí Minh. 2014;(18):473 - 478.
10. Trương Lê Tuấn Anh. Điều trị can thiệp đường động mạch trên bệnh nhân thiếu máu não cục bộ cấp. Luận văn tiến sĩ y học, Đại học Y Dược Thành phố Hồ Chí Minh. Published online 2016.
11. Park JS, Kwak HS. Manual aspiration thrombectomy using penumbra catheter in patients with acute m2 occlusion: a single - center analysis. J Korean Neurosurg Soc. 2016;59(4):352 - 356. doi:10.3340/jkns.2016.59.4.352
12. Bhogal P, Bücke P, Pérez MA, Ganslandt O, Bäzner H, Henkes H. Mechanical Thrombectomy for M2 Occlusions: A Single - Centre Experience. INE. 2017;6(3 - 4):117 - 125. doi:10.1159/000458161
13. Dorn F, Lockau H, Stetefeld H, et al. Mechanical Thrombectomy of M2 - Occlusion. J Stroke Cerebrovasc Dis. 2015;24(7):1465 - 1470. doi:10.1016/j.jstrokecerebrovasdis.2015.04.013
14. Adams HP, Davis PH, Leira EC, et al. Baseline NIH Stroke Scale score strongly predicts outcome after stroke: A report of the Trial of Org 10172 in Acute Stroke Treatment (TOAST). Neurology. 1999;53(1):126 - 131. doi:10.1212/wnl.53.1.126
15. Leys D, Pruvo JP, Godefroy O, Rondepierre P, Leclerc X. Prevalence and significance of hyperdense middle cerebral artery in acute stroke. Stroke. 1992;23(3):317 - 324. doi:10.1161/01.str.23.3.317
16. Abul - Kasim K, Selariu E, Brizzi M, Petersson J. Hyperdense middle cerebral artery sign in multidetector computed tomography: definition, occurrence, and reliability analysis. Neurol India. 2009;57(2):143 - 150. doi:10.4103/0028 - 3886.51282
17. Lee KY, Latour LL, Luby M, Hsia AW, Merino JG, Warach S. Distal hyperintense vessels on FLAIR: an MRI marker for collateral circulation in acute stroke? Neurology. 2009;72(13):1134 - 1139. doi:10.1212/01.wnl.0000345360.80382.69