Prevalence of hyperuricemia and relationships with serum uric acid at Hanoi medical university hospital

Kieu Hong Nhung, Ho Thi Kim Thanh, Nghiem Nguyet Thu

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Abstract

This is a cross-sectional study conducted on 700 adults between 18-60 years old  who presented at   Hanoi Medical University Hospital from October 2020 to April 2021 for periodical check up. The results showed : the average concentration of serum uric acid was 366.5 ± 100.6 µmol/l, the  prevalence of hyperuricemia was 31.1% in all the participants; the rate of hyperuricemia in males (46.5%) was higher than in females (7.3%). The overweight/obese group had a higher rate of hyperuricemia than the non-overweight/non-obese group (41.6% compared with 21.7%, p < 0.05). The prevalence of hyperuricemia in the group with metabolic syndrome was 53.8%;  in the group with dyslipidemia was 44.9%. There was strong positive correlation between serum uric acid and creatinine; average positive correlations with body mass index (BMI), waist circumference, blood pressure, triglycerides (0.3 < r < 0.5; p < 0.001); average negative correlation with HDL-c (r = - 0,32; p < 0,001); weak positive correlation with cholesterol, LDL-c, glucose (r < 0.3; p < 0.001). Thus, hyperuricemia is considered part of the metabolic syndrome with prevalence in one-third of adults.

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References

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