Giá trị tiên lượng của các thông số tinh dịch đồ đối với khả năng sinh sản của nam giới

Abstract

Semen analysis plays an important role in the assessment of male fecundity. However, the utility of the semen analysis parameters to determine fertility in men is still limited. Therefore, we performed a cross-sectional descriptive study on 203 fertile men (whose fivies or partners having natural pregnancy) and 1086 infertile men who visited Hanoi Medical University from January 2014 to December 2019, to determine the predictive value of semen parameters on male fertility. The results showed that the 2 groups had comparable age, bMI and smoking ratio were simillar between two groups. Testicular volume of infertile men was smaller than normal men (12.88 ± 3.59 mL compared with 13.68 ± 3.62 mL with p = 0.006). On the contrary, the level of FSH concentration was higher in men of the infertile group (5.56 ± 4.79 mUI/mL when compared with 4.61 ± 2.09 mUI/mL; p = 0.007). On semen analysis, we recognized that although the semen parameters in infertile group were within the normal range according to the threshold established by WHO (2010), they were still significantly lower than those in fertile group. Consequently, we believe that semen parameters had a poor ability to classify men fertility (AUC < 0.7 on ROC curve). Using threshold values of semen analysis according to WHO 2010 standards, we found that sperm concentration and progressive motility are valuable in predicting male infertility.