Clinical characteristics and risk factors for ventriculitis in patients with intraventricular hemorrhage undergoing external ventricular drainage
Main Article Content
Abstract
The purpose of this study was to investigate the clinical characteristics and the factors associated with external ventricular drainage (EVD) - related ventriculitis in patients with intraventricular hemorrhage (IVH) undergoing EVD. We did a retrospective observational study of patients with IVH undergoing EVD admitted to the Center for Emergency Medicine of Bach Mai Hospital in Hanoi, Vietnam between January 2015 and February 2021. Of 124 patients, 24.2% had EVD - related ventriculitis. On admission, the median Glasgow Coma Score was 7 (IQR: 6.00 - 8.75), and the mean serum glucose level was 9.61 (SD: 2.80) mmol/L. Hospital - acquired pneumonia occurred in 41.5% (51/123) of patients. In a multivariate analysis, hospital - acquired pneumonia (odds ratio, OR: 2.641; 95% confidence interval, CI: 1.056 - 6.602) was independently associated with an increased risk of EVD - related ventriculitis. Additionally, serum glucose level ≥11.10 mmol/L (OR: 2.618; 95% CI: 0.969 - 7.069) also tended to be related to patients with EVD - related ventriculitis. Thus, to decrease the rate of EVD - related ventriculitis, the prevention of EVD - related ventriculitis needs to be enhanced through improving both prevention and treatment of hospital - acquired pneumonia and treating hyperglycemia more optimally in patients with IVH undergoing EVD.
Article Details
Keywords
Acute hydrocephalus, EVD-related ventriculitis, External ventricular drainage, Hospital-acquired pneumonia, Intraventricular hemorrhage
References
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