Clinical characteristics, laboratory tests and spirometry of asthmatic children with obstructive sleep apnea
Main Article Content
Abstract
Inflammation disease of the airway such as obstructive sleep apnea and asthma are linked with each other. We conducted a cross-sectional descriptive examination on 54 asthmatic children from 6 to 17 years old, managed at the National Children's Hospital to determine the rate of obstructive sleep apnea and describe the clinical and subclinical characteristics of this special group. Obstructive sleep apnea was diagnosed by respiratory polygraphy. 29/54 (53.7%) asthmatic children of 8.38 years old have obstructive sleep apnea, of which 26/29 (89.65%) children had mild and moderate persistent asthma with increased FENO (21.55 ± 19).0 ppb). 17/29 (58.62%) asthmatic children had mild obstructive sleep apnea, moderate persistent asthmatic children had higher prevalence of moderate obstructive sleep apnea (41.38% vs 13.79%, p< 0.05). OSA diagnosis and treatment is essential for the management of asthmatic children.
Article Details
Keywords
Asthma, OSAS, FENO, children
References
2. Al-Shamrani A, Alharbi AS. Diagnosis and management of childhood sleep-disordered breathing. Clinical approach. Saudi Med J. 2020; 41(9): 916-929.
3. Kapur VK, Auckley DH, Chowdhuri S et al. Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: An American Academy of Sleep Medicine Clinical Practice Guideline. J Clin Sleep Med. 2017 Mar 15;13(3):479-504.
4. Nguyen-Hoang Y, Nguyen-Thi-Dieu T, Duong-Quy S. Study of the clinical and functional characteristics of asthmatic children with obstructive sleep apnea. J Asthma Allergy. 2017; 10: 285-292.
5. Damianaki A, Vagiakis E, Sigala I et al. The Co- existence of Obstructive Sleep Apnea and Bronchial Asthma: Revelation of a New Asthma Phenotype? J.Clin.Med. 2019; 8(9),1476.
6. Alharbi M, Almutairi A, Alotaibi D et al. The prevalence of asthma in patients with obstructive sleep apnoea. Prim. Care Respir. J. 2009, 18, 328–330. 15.
7. Lê Thị Tuyết Lan, Trần Văn Ngọc. Hình ảnh học và thăm dò chức năng hô hấp.2016. Nhà xuất bản y học, Hà Nội.
8. Duong-Quy S. Clinical Utility Of The Exhaled Nitric Oxide (NO) Measurement With Portable Devices In The Management Of Allergic Airway Inflammation And Asthma. J Asthma Allergy. 2019 Oct 7;12:331-341.
9. Bộ Y tế. Đo đa ký hô hấp. Hướng dẫn quy trình kỹ thuật nội khoa chuyên ngành hô hấp. Nhà xuất bản Y học, 2016. Tr 267-270.
10. Nguyen-Thi-Bich H, Duong-Thi-Ly H, Thom VT et al. Study of the correlations between fractional exhaled nitric oxide in exhaled breath and atopic status, blood eosinophils, FCER2 mutation, and asthma control in Vietnamese children. J Asthma Allergy. 2016 Sep 14;9:163-170.
11. Ferrando M, Braido F, Baiardini I et al. Prevalence and impact of rhinitis, sleep disordered breathing and OSA in asthmatic patients. Shortness of Breath. 2014; 2. 125-130.
12. Covar RA, Fuhlbrigge AL, Williams P et al. The Childhood Asthma Management Program (CAMP): contributions to the understanding of therapy and the natural history of childhood asthma. Curr Respir Care Rep.2012; 1, 243-250.
13. Đào Thị Hồng Diên, Lê Thị Minh Hương, Nguyễn Thị Diệu Thúy. Nghiên cứu kết quả test lảy da với các dị nguyên hô hấp trong nhà của bệnh nhi hen phế quản. Tạp chí Y học thực hành. 2013; 860, số 3/2013: 52-55.