Clinical and paraclinical features of hbv - infected pregnant women giving birth at Thai Nguyen National Hospital

Hoang Thi Ngoc Tram, Ho Cam Tu, Truong Van Vu, Bui Thu Huong Huong, Nguyen Tien Dung, Nguyen Thi Mo, Nguyen Duc Hinh

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Abstract

Some clinical and paraclinical characteristics description of HBV - infected pregnant women and umbilical cord blood test at Thai Nguyen National Hospital. HBsAg (+) pregnant women with one live fetus, full term until delivery, Study design the cross - sectional description, using SPSS 20.0 and R, Pearson correlation method, Fisher’s Anova Test. Results Mean age 27.6 ± 4.2, clinical symptoms not specific for hepatitis include edema, anorexia, fatigue; cesarean section rate accounted for 66.7%. Laboratory tests HBeAg(+) maternal blood accounted for 45%, HBV DNA ≥5E+07 copies/ml accounted for 33.3%; cord blood HBsAg(+) accounted for 53.3%, HBeAg(+) accounted for 38.2%. Maternal peripheral blood cell levels and cord blood were positively correlated in pregnant women with a load less than 5E+07 copies of HBV DNA/ml. Conclusion clinical symptoms in pregnant patients are not specific for hepatitis B diagnosis; In the group of pregnant women who have a viral of load < 5E+07 copies/ml, a significant positive correlation was found between PBMCs maternal and umbilical cord blood.ik

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