Hiệu quả của can thiệp thí điểm giảm sử dụng Methamphetamine trên bệnh nhân điều trị Methadone tại Hà Nội

Abstract

The study assessed the results of a pilot Methadone treatment program to reduce Methamphetamine use at two clinics in Hanoi. The study sample consisted of 111 patients, of whom 88 were at moderate riskand 23 were at high risk for Methamphetamine use. All patients participated in an 8-week intervention.. Comparing before and after the intervention,  the proportions of  positive urine test for Methamphetamine in the moderate risk group decreased from 8.0% to 3.7% (p = 0.07), and the proportions of  positive urine test for opioid decreased from 37.5% to 12.35% (p ≤ 0.001). In the high risk group, the proportions of positive urine test for Methamphetamine and Opioid decreased from 87.0% to 15.8% and from 43.5% to 15.8% (p ≤ 0.001), respectively. In the moderate risk group the risk of depression decreased from 21% to 11%; risk ofanxiety decreased from 21% to 9.9%; and risk of stress , , decreased from 37% to 17.3% (p < 0.05). In the high risk group, the risk for anxiety and stress decreased from 52.6% to 26.3% and from 89.5% to 47.4% (p < 0.05), respectively. Results suggested that behavioral interventions targeting Methamphetamine use among Methadone patients can significantly reduce substance use and improve mental health. More research is needed to evaluate the long-term effectiveness of the intervention and the feasibility of expanding the intervention model.