18. Comparison of residual curarization post laparoscopic surgery in patients with or without follow up by TOF Watch

Pham Quang Minh, Nguyen Thi Bach Duong

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Abstract

As laparoscopic surgery becomes increasingly popular, the abdominal inflating process introduces many changes to the cardiovascular and the respiratory systems. While ERAS recommends that anesthesiologist should use deep muscle relaxants in laparoscopic surgery to conteol the side effects, this method can cause the risk of residual muscle relaxation post surgery. The study aimed to compare the residual curarizative rate between patients with or without TOF Watch observation. This prospective study, randomized clinical trial on 60 patients was divided into 2 groups, at Viet Duc Hospital from April to November, 2017. Results: age, sex, ASA, operative time, anesthesia time, type of surgery were similar in the two groups. The group that was not monitored by the TOF Watch had a higher residual curarizative rate after extubation than the monitored group, the difference was statistically significant with p < 0.05 at time points 1, 10, 20 minute. At 30 minutes after extubation, both groups (3.33% in the monitored group compared with 13.13% in the unmonitored group) still had residual curatization. The unmonitored group had a higher rate of respiratory distress symptoms during the first 30 minutes postextubation, 2 patients (6.67%) in this group had SpO2 lower than 93%; the monitored group did not have any patient with respiratory distress. Conclusion: Patients monitored by TOF Watch had a lower residual curarizative rate after extubation, but the risk of re-curarization was not completely eradicated.

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