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Published: 2022-10-06
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DOI: https://doi.org/10.52852/tcncyh.v157i9.913
Issue
Vol. 157 No. 9 (2022)
Section
Các bài báo
How to Cite
Hằng, V. V. ., & Vân Anh, P. T. . (2022). 17. Anti-inflammatory and analgesic activities of Tecan capsules in experimental animal models. Journal of Medical Research, 157(9), 140-146. https://doi.org/10.52852/tcncyh.v157i9.913

17. Anti-inflammatory and analgesic activities of Tecan capsules in experimental animal models

Vu Viet Hang, Pham Thi Van Anh

Main Article Content

Abstract

 This study was done to investigate the analgesic and acute anti-inflammatory effects of Tecan capsules. The capsules were evaluated for analgesic activity using hot plate and acetic acid-induced writhing methods in Swiss mice. The pre-treatment with Tecan (1.44 capsules/kg and 4.32 capsules/kg doses) was able to inhibit the number of abdominal writhes in the animals, but this treatment did not affect the behavior of animals in the hot plate test. For the acute anti-inflammatory activity, carrageenan-induced peritonitis model was used in Wistar rats. A reduction in inflammatory exudate volume and cell migration was seen with all test doses (0.72 and 2.16 capsules/kg) evaluated. The results of this study suggested that Tecan capsules have acute anti-inflammatory and peripheral antinociceptive properties.

Article Details

Keywords

Tecan capsules, anti-inflammatory, analgesic

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