28. U trung biểu mô màng phổi ác tính - Tổng quan tài liệu và báo cáo ca bệnh

Abstract

Mesothelioma is a type of tumor arising from the mesothelial cells lining body cavities including the pleura, pericardium, peritoneum, and vagina. Most Malignant Pleural Mesothelioma (MPM) occur in the chest and are often related to a history of asbestos exposure. The 2015 WHO classification (updated 2021), MPM is divided into 3 groups (under the subtype): Epithelioid Mesothelioma (EM); Sarcomatoid Mesothelioma (SM) and mixed form. The diagnosis of MPM is challenging and there are many “traps”, especially in small biopsies. Recently, thanks to the development of immunohistochemistry, the definitive diagnosis has made many advances. Computed tomography of the chest helps guide the diagnosis and biopsy of the lung and pleura; Thoracic surgery can be used with the goal of obtaining diagnostic specimens and providing palliative treatment. We report a case of MPM, SM type confirmed by pathology and immunohistochemical staining at the National Lung Hospital. This review highlights what physicians need to know regarding the clinical presentation, radiographs, and histological features, as well as recent advances in immunohistochemistry in the diagnosis of this disease.