Article Sidebar

PDF (Tiếng Việt)
Published: 2022-06-15
Abstract Views: 385
Views PDF (Tiếng Việt): 596
DOI: https://doi.org/10.52852/tcncyh.v155i7.931
Issue
Vol. 155 No. 7 (2022)
Section
Các bài báo
How to Cite
Hoa, T. T. P. ., & Hà, N. M. . (2022). 20. Outcome analysis of day 3 frozen embryo transfer in in vitro fertilization patients. Journal of Medical Research, 155(7), 154-161. https://doi.org/10.52852/tcncyh.v155i7.931

20. Outcome analysis of day 3 frozen embryo transfer in in vitro fertilization patients

Tran Thi Phuong Hoa, Nguyen Manh Ha

Main Article Content

Abstract

Frozen embryo transfer is being widely used because of its high efficiency in terms of both in vitro fertilization outcomes and economy. This study aimed to analyze the outcomes and related factors of day 3 frozen embryo transfer. This retrospective study carried out on 183 patients who underwent intracytoplasmic sperm injection (ICSI) cycles in the Center of IVF and Tissue engineering, Hanoi Medical University Hospital between January 2018 and December 2020. The results showed the majority of cases were transferred 2 embryos (131 patients accounted for 71.6%), and 3 embryos transfers were 28.4%. The numbers of grade 1 embryos in the 2 embryos transfer group was significantly higher than that of the 3 embryos transfer group (50.9% vs 26.3%, respectively; p < 0.05). The clinical pregnancy rate in both groups was 61.2% and the rate of multiple pregnancies was 21.9%. The quality of embryo transfer affects IVF outcomes, the chance of clinical pregnancy in 1 potential embryo transfer group decreased significantly by 0.368 times compared with the 2 potential embryos group (95%CI: 0.174 - 0.781).

Article Details

Keywords

in vitro Fertilization, Day 3 frozen embryo transfer

References

1. Shi Y, Sun Y, Hao C, et al. Transfer of fresh versus frozen embryos in ovulatory women. N Engl J Med. 2018;378(2):126-136. doi: 10.1056/NEJMoa1705334.
2. Alpha scientists in reproductive medicine and ESHRE special interest group of embryology. The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting. Hum Reprod Oxf Engl. 2011;26(6):1270-1283. doi: 10.1093/humrep/der037.
3. De Geyter C, Calhaz-Jorge C, Kupka MS, et al. ART in Europe, 2015: results generated from European registries by ESHRE. Hum Reprod Open. 2020;2020(1):hoz038. doi: 10.1093/hropen/hoz038.
4. The European IVF-monitoring Consortium (EIM) for the European Society of Human Reproduction and Embryology (ESHRE), Wyns C, Bergh C, et al. ART in Europe, 2016: results generated from European registries by ESHRE. Hum Reprod Open. 2020;2020(3). doi: 10.1093/hropen/hoaa032.
5. The European IVF-Monitoring Consortium (EIM) for the European Society of Human Reproduction and Embryology (ESHRE), Wyns C, De Geyter C, et al. ART in Europe, 2017: results generated from European registries by ESHRE. Hum Reprod Open. 2021;2021(3). doi: 10.1093/hropen/hoab026.
6. Nguyễn Thị Minh Khai. Đánh giá hiệu quả chuyển phôi trữ đông cho bệnh nhân thụ tinh trong ống nghiệm tại Bệnh viện Phụ sản Trung ương giai đoạn 2012-2014. Published online 2017. https://sdh.hmu.edu.vn/images/NGUYENTHIMINHKHAI-LA.pdf.
7. Lu SE, Xu M, Lu S, et al. Analysis of factors affecting live birth outcome of frozen-thawed embryo transfer cycle. Zhonghua Yi Xue Za Zhi. 2021;101(32):2552-2558. doi: 10.3760/cma.j.cn112137-20210318-00684.
8. Veleva Z, Orava M, Nuojua-Huttunen S, Tapanainen JS, Martikainen H. Factors affecting the outcome of frozen-thawed embryo transfer. Hum Reprod Oxf Engl. 2013;28(9):2425-2431. doi: 10.1093/humrep/det251.