23. Factors associated with treatment discontinuation among people receiving buprenorphine in three mountanous provinces in North Vietnam

Dao Thi Dieu Thuy, Vu Minh Anh, Dinh Thi Thanh Thuy, Nguyen Thu Trang, Le Minh Giang

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Abstract

This is a cohort study performed to explore associated factors with opioid treatment discontinuation among people receiving buprenorphine. 130 patients receiving buprenorphine in 3 mountainous provinces in north Vietnamparticipated in the study. Inclusion criteria included: 16 years old or older, buprenorphine initiated between Sep 2019 and Dec 2019, and volunteered to participate the study. Data sources included extracting monthly data from medical records and face-to-face interviews at two time points, Jun 2020 and Sep 2020. Our findings showed the discontinuation rates at the 6 months, 9 months, and 12-months after starting buprenorphine were 11.5%, 21.5% and 26.2%, respectively. Older age, (aOR = 0.9, 95%CI: 0.87 - 0.97), participating in counselling sessions at clinics (aOR = 0.25, 95%CI: 0.12 - 0.52) decreased the hazards of discontinuation in buprenorphine. Being female increased the hazard of discontinuation compared to male (aOR = 4.2, 95%CI: 1.06 - 16.69). Our study highlighted the importance of counselling sessions in retaining patients on buprenorphine. More studies are needed to address risk factors of treatment discontinuation and improve the retention of patients receiving buprenorphine treatment.

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References

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