Enucleation thoracoscopic and laparoscopic for esophageal leiomyoma

Nguyễn Thị Bích Ngọc, Đặng Hồng Hoa, Nguyễn Vĩnh Ngọc

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Abstract

The level of increased IL6 may be considered as a predictor of joint damage on ultrasound of patients with primary osteoarthritis. Study methods: Cross - sectional descriptive study with 26 patients diagnosed with knee osteoarthritis according to ACR1991 standards at the Department of Rheumatology, E Hospital. The collected research information included: clinical (age, sex, ailment duration), subclinical (Protein C reactive - CRP, IL - 6) and knee ultrasound characteristics including cartilage thickness and condition of the synovial fluid. IL - 6 is considered to be increased when > 7 pg/ml. Research results: 26 patients (45 knee joints) were selected for the study. The average age of the research group was 64.1 ± 11.4, of which the most co mmon age group was 60 - 69 with female representing 88.5%. The main range of condition is 1 - 5 years, accounting for 50.0% and > 5 years, accounting for 46.2%. Ultrasound revealed joint cartilage thickness ( mm) LLC was 1.95 ± 0.46; LCN was 1.91 ± 0.51 and LCT was 1.85 ± 0.51. 30/45 patients had thickened synovial fluid accounting for 66.7% and 30/45 patients had synovial fluid accounting for 66.7%. The results showed a relationship between the synovial fluid thickness of knee, CRP index and IL - 6 concentration (p < 0.05). In conclusion, we had determined a relationship between plasma concentrations of IL6 with synovial fluid thickness on ultrasound and CRP levels in patients with primary osteoarthritis.

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References

1. Berenbaum F. Osteoarthritis as an infla mmatory disease (osteoarthritis is not osteoarthrosis!). Osteoarthritis Cartilage 2013;21: 16 - 21.
2. Roemer FW, Kassim Javaid M, Guermazi A, et al. Anatomical distribution of synovitis in knee osteoarthritis and its association with joint effusion assessed on non - enhanced and contrast - enhanced MRI. Osteoarthritis Cartilage 2010;18: 1269 - 1274.
3. Loeuille D, Rat AC, Goebel JC, et al. Magnetic resonance imaging in osteoarthritis: which method best reflects synovial membrane infla mmation? Correlations with clinical, macroscopic and microscopic features. Osteoarthritis Cartilage 2009;17: 1186 - 1192.
4. O’Neill TW, Parkes MJ, Maricar N, et al. Synovial tissue volume: a treatment target in knee osteoarthritis (OA). Ann Rheum Dis 2015.
5. Pearle AD, Scanzello CR, George S, et al. Elevated high - sensitivity C - reactive protein levels are associated with local infla mmatory findings in patients with osteoarthritis. Osteoarthritis Cartilage. 2007;15 (5): 516 - 523.
6. Sacitharan PK. Ageing and Osteoarthritis. Subcell Biochem. 2019;91: 123 - 159.
7. Freemont AJ, Abdellatif E. Synovial fluid analysis. In: Hochberg MC, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH. Rheumatology. 6th ed. Philadelphia: Elsevier; 2015. 237 - 241.
8. Hirsch G, Kitas G, Klocke R. Intra - articular corticosteroid injection in osteoarthritis of the knee and hip: factors predicting pain relief asystematic review. Semin ArthritisRheum 2013;42: 451 - 73.
9. Pyne, D., Intra - articular steroids in knee osteoarthritis: a comparative study of triamcinolone hexacetonide and methylprednisolone acetate. Clin Rheumatol, 2004. 23 (2): 116 - 120.
10. McCabe, P.S., Brief Report: Synovial Fluid White Blood Cell Count in Knee Osteoarthritis: Association With Structural Findings and Treatment Response. Arthritis Rheumatol, 2017. 69 (1): 103 - 107.