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Published: 2025-02-27
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DOI: https://doi.org/10.52852/tcncyh.v187i2.3013
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Vol. 187 No. 2 (2025)
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Các bài báo
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Luân, N. T., Tảo, N. Đình, Hằng, T. T. T., Anh, T. T. V., Thuỷ, T. T., Thịnh, N. V., Sơn, T. T., & Hùng, H. S. (2025). 12. The effectiveness of progestin-primed ovarian stimulation (PPOS) protocol at the National Hospital of Obstetrics and Gynecology. Journal of Medical Research, 187(2), 101-107. https://doi.org/10.52852/tcncyh.v187i2.3013

12. The effectiveness of progestin-primed ovarian stimulation (PPOS) protocol at the National Hospital of Obstetrics and Gynecology

Nguyen Thanh Luan, Nguyen Dinh Tao, Tran Thi Thu Hang, Tran Thi Van Anh, Tran Thi Thuy, Ngo Van Thinh, Trinh The Son, Ho Sy Hung

Main Article Content

Abstract

This is a retrospective cross-sectional study evaluating the oocyte and fertilization results of the PPOS (Progestin Primed Ovarian Stimulation) regimen at the Central Obstetrics HospitalThe PPOS protocol regimen uses progesterone to suppress premature LH surge and reduce the rate of ovarian hyperstimulation syndrome (OHSS) was applied in in- vitro fertilization. Data from 106 ovarian stimulation cycles were collected and analyzed.The mean age of the study group was 32.8 ± 6.1 years old. Baseline FSH value: 7.1 ± 4.0 mIU/L, baseline LH: 5.4 ± 2.6 mIU/L; mean AFC and AMH index: 1.4 ± 8.6 follicles and 3.17 ± 2.87 ng/mL. Mean ovarian stimulation duration: 9.6 ± 1.2 days, mean total FSH dose: 2089.2 ± 621.7 (IU). LH and E2 concentrations on trigger day: 5.2 ± 4.3 U/L and 4616.9 ± 3858.9 pg/mL. Number of follicles larger than 14mm: 12.8 ± 8.5 follicles. No case of moderate and severe ovarian hyperstimulation was recorded. Average number of retrieved oocytes: 12.5 ± 8.2 oocytes, average number of GV oocytes: 2.8 ± 4.6, MI oocytes: 1.1 ± 1.5, MII oocytes: 8.6 ± 6.6. Average number of ICSI oocytes and fertilized oocytes: 9.3 ± 6.8 and 7.7 ± 5.7.

Article Details

Keywords

Infertility, IVF, PPos, ovarian stimulation

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