Bệnh viêm hạch Kikuchi ở trẻ em: Báo cáo ca bệnh và tổng quan tài liệu

Abstract

Kikuchi-Fujimoto disease is a rare condition in children, characterized by necrotizing lymphadenitis and fever, often associated with immune dysregulation, and a definitive diagnosis relies on histopathological examination of lymph node tissue. We report a case of an 11-years-old girl who presented with a 12-day history of fever and painful left cervical lymphadenopathy. Prior fine-needle aspiration (FNA) revealed necrotizing lymphadenitis, however the patient did not respond to empirical antibiotic therapy. Autoimmune screening was inconclusive. An excisional lymph node biopsy was performed, confirming the diagnosis of Kikuchi-Fujimoto disease. The patient became afebrile after three weeks of treatment, was discharged and found stable at the 2 weeks follow-up. Conclusion: Kikuchi-Fujimoto disease is a rare but self-limiting inflammatory condition in pediatric patients. A definitive diagnosis requires histopathological evaluation of excised lymph node tissue. Management is primarily supportive. Due to the risk of recurrence, post-discharge follow-up is recommended.